J Plast Reconstr Aesthet Surg
July 2024
Background: The efficient resurfacing of multiple adjacent defects (MADs) requires precise reconstructive strategy. Various approaches (e.g.
View Article and Find Full Text PDFInt Immunopharmacol
November 2023
In reconstructive and plastic surgery, random skin flaps are commonly utilized to treat skin abnormalities produced by a variety of factors. Flap delay procedure is commonly used to reduce flap necrosis. Due to the limitations of various conditions, the traditional surgical improvement can't effectively alleviate the skin flap necrosis.
View Article and Find Full Text PDFIn this work, the defective Cu-BDC with different defect concentration and Cu/Cu coordinatively unsaturated sites (CUS) content were designed and synthesized by introducing defective linkers with different p values. The low-concentration defects in Metal-organic frameworks (MOFs) structure act as the active sites to enhance their photocatalytic activity. In contrast, the high concentration defects serve as the recombination centers of photogenerated electrons and holes to decrease the transfer efficiency of charge carriers.
View Article and Find Full Text PDFRandom skin flaps are often used in reconstruction operations. However, flap necrosis is still a common postoperative complication. Here, we investigated whether berberine (C H NO , BBR), a drug with antioxidant activity, improves the survival rate of random flaps.
View Article and Find Full Text PDFBackground: Skin flap transplantation is a common wound repair method in orthopedic surgery, but skin flap necrosis remains problematic. Memantine, an excitatory amino acid receptor antagonist, is currently used in the treatment of moderate to severe Alzheimer's disease, due to its ability to promote angiogenesis and reduce oxidative stress. This study investigated the effect of memantine on the survival of random skin flaps in Sprague-Dawley (SD) rats.
View Article and Find Full Text PDFA novel magnetic porous carbon with a high specific surface and magnetization saturation, derived from a Zn/Co-MOF-5, was fabricated by direct carbonization of Zn/Co-MOF-5 without the need of additional carbon precursors under optimum pyrolysis temperature. The material was employed as an adsorbent for magnetic solid-phase extraction of four carbamates from water and tomato samples prior to high-performance liquid chromatography-tandem quadrupole mass spectrometry analysis. Under optimum conditions, the method displayed good linearity (r > 0.
View Article and Find Full Text PDFFe3O4/VAN@MIL-101(Fe) with both mesoporous and mixed-valence Fe3+/Fe2+ structures was controllably synthesized in the synthesis of MIL-101(Fe), and it was used as a bifunctional photocatalyst in both oxygen evolution reactions (OERs) and hydrogen evolution reactions (HERs) of photocatalytic water splitting. By the reduction of auxiliary ligand vanillin (VAN) and the introduction of Fe3O4, the mixed-valence Fe3+/Fe2+ structure in Fe3O4/VAN@MIL-101(Fe) was obtained, which improves the band gap of the Fe3+ reactive active center and increases the separation efficiency of photogenerated carriers. Owing to the partial difference in the structure between VAN and ligand terephthalic acid (H2BDC), hierarchical porous and vacant structures were effectively improved in Fe3O4/VAN@MIL-101(Fe), which can induce more active sites to adsorb more water molecules and shorten the electron-hole migration distance to improve the transfer efficiency of photogenerated carriers.
View Article and Find Full Text PDFPurpose: This study aimed to compare and analyze the outcomes of finger reconstruction using free distal ulnar artery perforator (FDUAP) and reverse dorsal homodigital island (RDHI) flaps.
Methods: The study included 27 patients with finger pulp defects that were reconstructed using FDUAP or RDHI flaps. Standardized assessment of outcomes included objective sensory recovery, duration of operation, range of motion in the repaired fingers, pain at the reconstructed finger pulps and donor sites, and recovery time before returning to work.
Int Immunopharmacol
November 2019
Background: Random flaps are commonly used to repair wounds and improve the clinical appearance. However, flap necrosis is frequently encountered in the clinical setting. Adiponectin is a biologically active endogenous polypeptide secreted by adipocytes that can reduce oxidative stress, inflammation, and apoptosis.
View Article and Find Full Text PDFNecrosis in distal areas of random skin flaps remains a challenging issue. Curculigoside A (CA), one of the main bioactive phenolic compounds, has been reported to induce angiogenesis in vitro by increasing proliferation, tube formation, and migration. In addition, CA was shown to increase vascular endothelial growth factor (VEGF) expression.
View Article and Find Full Text PDFBackground: Random-pattern flap transfer is commonly used to treat soft-tissue defects. However, flap necrosis remains a serious problem. Naringin accelerates angiogenesis by activating the expression of vascular endothelial growth factor (VEGF).
View Article and Find Full Text PDFJ Orthop Surg Res
November 2017
Background: Reconstruction of chronic lower extremity wounds remains challenging. These wounds are mainly associated with diabetes mellitus, infections, and osteomyelitis. Although several reconstructive techniques are available, the peroneal artery perforator flap has unique advantages.
View Article and Find Full Text PDFBackground: Tirofiban is a glycoprotein IIb/IIIa receptor antagonist that is widely used clinically. In the present study, we investigated whether tirofiban promotes flap survival in rat random skin flap model.
Methods: "McFarlane flaps" models were developed in 60 male rats.