Comparative analysis of antioxidant activity and structural changes of polysaccharides between sulfur-fumigation and nonsulfur-fumigation.

Introduction: (referred to Tianma in Chinese), the dried tuber of Bl. (Orchidaceae), is utilized as a medicine-food homology product. Sulfur fumigation is commonly employed in the processing of (GR).

Comammox Nitrospira are the dominant ammonia oxidizers in the Yangtze estuarine biofilms.

Biofilms are indispensable ecological habitats for microbes that have garnered global attention and play a potential role in influencing the biogeochemical cycling of nitrogen. However, the biogeochemical significance of biofilms and the mechanisms by which they regulate nitrogen cycling remain elusive. In this study, we utilized DNA-stable isotope probing (DNA-SIP) labelling techniques in conjunction with metagenomics to reveal a nitrifying ecological niche in biofilms taken from the Yangtze Estuary, with those from sediment and water samples for comparison.

Program-Modulated Kinetics of Perovskite-Film Growth by Molecular "Thruster" for High-Efficiency and Stable Perovskite Solar Cells.

The rapid reaction between lead iodide (PbI2) and formamidinium iodide (FAI) complicates the fabrication of high-quality formamidinium lead iodide (FAPbI3) films. Conventional methods, such as using nonvolatile small molecular additives to slow the reaction, often result in buried interfacial voids and molecule diffusion, compromising the devices' operational stability. In this study, we introduced a molecular "thruster"-a hypervalent iodine (III) compound with three carbonyl groups and a C--I⁺ bond-that possesses coordination and dissociation abilities, enabling programed modulation of perovskite-film growth kinetics.

METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism.

The persistent airway inflammation is the main characteristic of chronic obstructive pulmonary disease (COPD), typically caused by an indoor environment pollution cigarette smoke (CS). METTL16 is an mA methyltransferase that has been proven to be closely associated with the occurrence of various diseases. However, its exact role in smoking-induced COPD remains to be investigated.

Enhanced osteo-angiogenic coupling by a bioactive cell-free fat extract (CEFFE) delivered through electrospun fibers.

Regeneration of functional bone tissue relies heavily on achieving adequate vascularization in engineered bone constructs following implantation. This process requires the close integration of osteogenesis and angiogenesis. Cell-free fat extract (CEFFE or FE), a recently emerging acellular fat extract containing abundant growth factors, holds significant potential for regulating osteo-angiogenic coupling and promoting regeneration of vascularized bone tissue.

Dual-Functional Passivation Agent of Natural Dye Congo Red For Enhanced Carbon-Based Perovskite Solar Cells.

Carbon-based perovskite solar cells (C-PSCs) have acquired broad interest due to their superior stability and lower cost compared with metal-based perovskite solar cells (M-PSCs). However, the presence of perovskite defects greatly limits the power conversion efficiency (PCE) and long-term stability of C-PSCs. Herein, a natural dye Congo red molecule containing dual-functional groups of amino and sulfonic acids is first used as a surface passivation agent to treat the surface of perovskite films.

Development and validation of a nomogram-based risk prediction model for carbapenem-resistant in hospitalized patients.

Carbapenem-resistant (CRKP) poses one of the major challenges in clinical anti-infective therapy worldwide. This retrospective cohort study at a tertiary general hospital in Wuhan aimed to identify risk factors for hospital-acquired CRKP infections among 1,113 patients. All participants were aged 18 years and above, and had confirmed positive cultures for KP isolated within 48 hours post-hospitalization.

Unlocking the Ultrafast Deposition Kinetics within Bi-Tailored Core-Shell Structured Carbon Nanofibers for Highly Efficient and Ultrastable Sodium Metal Batteries.

Sodium metal anodes (SMA), featuring high energy content, low electrochemical potential and easy availability, are a compelling option for sustainable energy storage. However, notorious sodium dendrite and unstable solid-electrolyte interface (SEI) have largely retarded their widespread implantation. Herein, porous amorphous carbon nanofiber embedded with Bi nanoparticles in nanopores (Bi@NC) was rationally designed as a 3D host for SMA.

[Characteristics, Transport Routes, and Potential Sources of PM and O Pollution in Suzhou].

Based on the air quality and meteorological data in Suzhou from 2015 to 2022, the long-term variations in PM and O, meteorological characteristics, and their correlations were analyzed in this study. The HYSPLIT model was used to explore the main transport pathways and potential source areas of PM and O. The results showed that： ① The annual averaged concentrations of PM in Suzhou decreased steadily during the study period, and the annual average concentration from 2020 to 2022 reached the national second-level standard limit.

Validation of the Node Reporting and Data System (Node-RADS) for standardized CT evaluation of regional lymph nodes in esophageal squamous cell carcinoma patients.

Objectives: The accurate identification of positive lymph nodes in esophageal squamous cell carcinoma (ESCC) influences patient risk assessment and treatment decisions, but there is no standardized approach for radiological evaluation. The aim of this study was to verify the diagnostic performance of the new Node Reporting and Data System 1.0 (Node-RADS) in the assessment of lymph node metastasis in patients with ESCC, as verified by final histopathology.

Discovery of the First BRD4 Second Bromodomain (BD2)-Selective Inhibitors.

Pan-BD2 inhibitors have been shown to retain an antileukemia effect and display less dose-limiting toxicities than pan-BET inhibitors. However, it is necessary to consider the potential off-target toxicity associated with the inhibition of four BET BD2 proteins. To date, no BRD4 BD2 domain selective inhibitor has been reported.

CCT39-COMT1/BGLU18-2 module promotes lignin biosynthesis in poplar.

Lignin is a crucial constituent of cell walls and plays a pivotal role in plant growth and development. However, the transcriptional regulatory network governing lignin biosynthesis is not fully understood. In this study, we observed that PpnCCT39 overexpression resulted in greener stems, larger basal diameters, and increased stem dry weight.

Dicyclopenta[4,3,2,1-cde:4',3',2',1'-pqr]-peri-tetracene: Synthesis and an Example of Annulene-within-an-Annulene Aromaticity in Different Redox States.

We report a robust strategy for tuning the electronic structure and chemical stability of π-conjugated polycyclic hydrocarbons (PHs). By fusing two cyclopentadienyl rings in the peri-tetracene bay regions, we introduce antiaromatic character into the π-system, leading to unique photophysical and electronic properties. A stable mesityl-substituted dicyclopenta-peri-tetracene derivative was synthesized through stepwise formylation/intramolecular cyclization at the bay regions of the dihydro peri-tetracene precursor, followed by oxidative dehydrogenation.

Optimized Carbon Coupling for Enhanced Ethylene Production via a Unique Single-Atom-Substrate Synergy Mechanism within Photocatalytic Processes.

The utilization of solar-driven technologies for the direct conversion of methanol (CHOH) into two or multi-carbon compounds through controlled carbon-carbon (C-C) coupling is an appealing yet challenging objective. In this study, we successfully demonstrate the photocatalytic CHOH coupling to ethylene (CH), a valuable chemical raw material, by employing a carbon nitride-based catalyst. Specifically, we modify the layered polymer carbon nitride (PCN) photocatalyst through the incorporation of Au single atoms (Au/PCN) using a chemical-scissors method.

Liquid biopsy with plasma Epstein-Barr virus DNA characterizes biological relapse for the prediction of cancer recurrence in non-disseminated nasopharyngeal carcinoma.

Purpose: To investigate whether a bounce in plasma Epstein-Barr virus (EBV) DNA during posttreatment surveillance of nasopharyngeal carcinoma (NPC) informs the risk of clinical recurrence and its implication for early therapeutic intervention.

Methods: 950 non-disseminated NPC patients with completed remission in 3 months after treatment were retrospectively screened. Detectable EBV DNA with no evidence of clinical relapse during follow-up was deemed as DNA bounce.

Novel plasmid-mediated CMY variant (CMY-192) conferring ceftazidime-avibactam resistance in multidrug-resistant .

The rapid rise of multidrug resistance (MDR) among Gram-negative bacteria has accelerated the development of novel therapies. Ceftazidime-avibactam (CZA) is a novel β-lactam/β-lactamase inhibitor recently approved for the treatment of limited infectious diseases. Here, we describe a novel CMY variant, CMY-192, that confers high-level resistance to CZA.

Dibenzo-peri-Heptacene: A Stable Open-Shell Graphene Fragment With a Balanced Combination of Armchair and Zigzag Edge Structures.

Atomically precise open-shell graphene fragments, such as extended peri-acenes, hold significant interest for electronics and spintronics. However, their inherent high reactivity poses challenges for synthesis and application. In this study, a novel approach is introduced: the fusion of a zigzag-edged peri-tetracene with an all-armchair-edged hexa-peri-hexabenzocoronene (HBC) via two shared benzene rings to produce a stable open-shell hydrocarbon, named dibenzo-peri-heptacene (DBPH).

Measurements of enteral feeding intolerance in critically ill children: a scoping review.

Objective: To examine the measurements on enteral feeding intolerance (EFI) in critically ill children.

Methods: The Joanna Briggs Institute methods for conducting a scoping review were followed. Articles published since 2004 which assessed EFI in critically ill children were identified.

Association between healthy lifestyle on life course and multimorbidity in adults: results from two national prospective cohort studies.

Objectives: To examine the correlation between healthy lifestyle patterns, their change trajectories, and the risk of multimorbidity in adults.

Methods: Based on two representative national cohorts, the English Longitudinal Study of Aging (ELSA) and the Health and Retirement Study (HRS) including adults aged 50 years and over. We employed Cox regression, lifestyle change trajectories, and restricted mean survival times to explore the relationship between lifestyle (assessed by SCORE2, LE'8, and HLS scores) and multimorbidity.