Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms.

The escalating hazards posed by bacterial infections underscore the imperative for pioneering advancements in next-generation antibacterial modalities and treatments. Present therapeutic methodologies are frequently impeded by the constraints of insufficient biofilm infiltration and the absence of precision in pathogen-specific targeting. In this current study, we have used chlorin e6 (Ce6), zeolitic imidazolate framework-8 (ZIF-8), polydopamine (PDA), and UBI peptide to formulate an innovative nanosystem meticulously engineered to confront bacterial infections and effectually dismantle biofilm architectures through the concerted mechanism of photodynamic therapy (PDT)/photothermal therapy (PTT) therapies, including in-depth research, especially for oral bacteria and oral biofilm.

Silk fibroin-gelatin photo-crosslinked 3D-bioprinted hydrogel with MOF-methylene blue nanoparticles for infected wound healing.

Photo-crosslinked hydrogel (PH) is an outstanding candidate for three-dimensional (3D) printing as a wound dressing because of its high efficiency in crosslinking and injectability. In this study, methylene blue (MB)-loaded UiO-66(Ce) nanoparticles (NPs) were synthesized to prevent drug self-aggregation and achieve the photodynamic therapy (PDT) effect for efficient antibacterial action. Then, a composite photocrosslinked silk fibroin (SF)/gelatin hydrogel loaded with MB@UiO-66(Ce) NPs (MB@UiO-66(Ce)/PH) was fabricated.

Multifunctionalized carbon-fiber-reinforced polyetheretherketone implant for rapid osseointegration under infected environment.

Carbon fiber reinforced polyetheretherketone (CFRPEEK) possesses a similar elastic modulus to that of human cortical bone and is considered as a promising candidate to replace metallic implants. However, the bioinertness and deficiency of antibacterial activities impede its application in orthopedic and dentistry. In this work, titanium plasma immersion ion implantation (Ti-PIII) is applied to modify CFRPEEK, achieving unique multi-hierarchical nanostructures and active sites on the surface.

A pilot study on the use of a novel digital real-time evaluation system in undergraduate preclinical training of tooth preparation in fixed prosthodontics.

Introduction: In the light of the digital teaching, it is necessary that the effectiveness of a new digital real-time evaluation system in the preclinical training of tooth preparation be evaluated.

Materials And Methods: Forty undergraduate dental students of the fourth year were randomly divided into the control group and the experimental group to complete the training task of tooth preparation for porcelain fused to metal (PFM) crown restoring the upper right central incisor. The control students received conventional training with instructor's guidance.

Promoting lacunar bone regeneration with an injectable hydrogel adaptive to the microenvironment.

Injectable hydrogel is suitable for the repair of lacunar bone deficiency. This study fabricated an injectable, self-adaptive silk fibroin/mesoporous bioglass/sodium alginate (SMS) composite hydrogel system. With controllable and adjustable physical and chemical properties, the SMS hydrogel could be easily optimized adaptively to different clinical applications.

Exploring the optimal pre-sintering temperature on compressive strength and anti-fatigue property of graded zirconia-based glass/zirconia structure.

To explore the optimal pre-sintering temperature for graded glass/zirconia material, glass/zirconia specimens were prepared and pre-sintered at 900, 1,000 and 1,100°C respectively, glass infiltration and densification at 1,450°C. Monolith Y-TZP specimens were sintered at 1,450°C. Nanoindentation was used to test Young's modulus and Hardness.

Comparison of marginal and internal fit of 3-unit ceramic fixed dental prostheses made with either a conventional or digital impression.

Statement Of Problem: For 20 years, the intraoral digital impression technique has been applied to the fabrication of computer aided design and computer aided manufacturing (CAD-CAM) fixed dental prostheses (FDPs). Clinical fit is one of the main determinants of the success of an FDP. Studies of the clinical fit of 3-unit ceramic FDPs made by means of a conventional impression versus a digital impression technology are limited.

Comparison of repeatability between intraoral digital scanner and extraoral digital scanner: An in-vitro study.

Purpose: The aim of this study was to compare the repeatability of intraoral digital impression scanning with the repeatability of extraoral scanning by using Geomagic Qualify 12 as the software of analysis.

Methods: One Nissin Dental Study Model (upper jaw) with prepared abutments were designed to form 5 set of arrangements according to the layout of prepared abutments (arrangement 1: single prepared maxillary central incisor; arrangement 2: single prepared maxillary first molar; arrangement 3: prepared central incisor and canine with the lateral incisor absent; arrangement 4: half of upper arch with 7 prepared teeth; arrangement 5: entire upper arch with 14 prepared teeth). Each arrangement of Nissin Dental Study Model was scanned by TRIOS intraoral digital scanner (experimental group) and D800 extraoral scanner (control group) for 10 times exporting 100 STL files in total.

Intraoral Digital Impression Technique: A Review.

With the techniques of computer-aided design and computer-aided manufacturing (CAD/CAM) being applied in the field of prosthodontics, a concept of intraoral digital impressions was put forward in the early 1980s. It has drawn comprehensive attention from dentists and has been used for dental prosthesis fabrication in a number of cases. This new digital impression technique is expected to bring about absolute digitization to the mode of prosthodontics.