Identification and Functional Characterization of a Novel Immunomodulatory Protein From SH.

A novel fungal immunomodulatory protein (FIP) was found in the precious medical and edible mushroom SH, defined as FIP-mco, which belongs to the FIP family. Phylogenetic analyses of FIPs from different origins were performed using Neighbor-Joining method. It was found that FIP-mco belonged to a new branch of the FIP family and may evolved from a different ancestor compared with most other FIPs.