Publications by authors named "Tingsha Du"
Article Synopsis
- This study examines the effectiveness and safety of pulsed field ablation (PFA) for treating atrioventricular nodal reentrant tachycardia (AVNRT), focusing on its impact on dual-pathway electrophysiology.
- All 40 patients achieved acute success with PFA, showing an average total ablation time of 7.9 seconds, and 80% experienced induced slow junctional rhythm; however, there were instances of transient atrioventricular block in 17.5% of patients.
- The study concludes that while PFA is highly effective for slow pathway modification, there are risks of transient AV block, especially when performed close to the His bundle,
Article Synopsis
- Doxorubicin (DOX) is limited in its clinical use due to cardiotoxicity caused by oxidative stress and inflammation, while the role of Sulfiredoxin 1 (Srxn1) in this process is not well understood.* -
- In this study, researchers overexpressed Srxn1 in mice and found that it improved cardiac function and reduced injury by decreasing oxidative stress and inflammation caused by DOX treatment.* -
- The study concluded that Srxn1 protects against DOX-induced cardiac damage by modulating the Sirt1/NLRP3 signaling pathway, suggesting it could be a promising therapeutic target for preventing myocardial injury from DOX.*
Diabetic cardiomyopathy (DCM) is characterized by oxidative damage and inflammatory responses. Myeloid differentiation protein 1 (MD1) exhibits antioxidant and anti-inflammatory properties. However, the specific role of MD1 in DCM has yet to be elucidated.
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