SIRT1 deacetylates mitochondrial trifunctional enzyme α subunit to inhibit ubiquitylation and decrease insulin resistance.

Dysregulation of free acid metabolism is a major contributor to the development of insulin resistance and diabetes. Mitochondrial trifunctional enzyme subunit (MTPα) has a critical role in fatty acid β-oxidation. However, the association between MTPα and insulin resistance is not definitively known.

Fracture Mechanics Method for Word Embedding Generation of Neural Probabilistic Linguistic Model.

Word embedding, a lexical vector representation generated via the neural linguistic model (NLM), is empirically demonstrated to be appropriate for improvement of the performance of traditional language model. However, the supreme dimensionality that is inherent in NLM contributes to the problems of hyperparameters and long-time training in modeling. Here, we propose a force-directed method to improve such problems for simplifying the generation of word embedding.

A novel ultrasonic thermotherapy instrument.

An structure is proposed for fabricating a portable prototype apparatus, using the embedded control technique based on ARM core, which has a simple structure and small size. The hardware is easily updated and maintained due to its modular structure, the software has a visualized interface and hierarchical design mode, so the apparatus has a good peculiarity like compact structure and control. Moreover, the build-in PID algorithm for temperature control and the power driver element for ultrasonic output power have been optimized the experiment results demonstrate that using this structure and optimization method.