Microscopy and spatial-metabolomics identify tissue-specific metabolic pathways uncovering salinity and drought tolerance mechanisms in Avicennia marina and Phoenix dactylifera roots.

In arid and semi-arid climates, native plants have developed unique strategies to survive challenging conditions. These adaptations often rely on molecular pathways that shape plant architecture to enhance their resilience. Date palms (Phoenix dactylifera) and mangroves (Avicennia marina) endure extreme heat and high salinity, yet the metabolic pathways underlying this resilience remain underexplored.

The Effect of Traditional Chinese Medicine Treatment on the Cumulative Live Birth Rate of Patients with Poor Ovarian Response to the Patient-Oriented Strategies Encompassing Individualized Oocyte Number Criteria.

Objective: This study analyzed the role of traditional Chinese medicine (TCM) treatment on the cumulative live birth rate (CLBR) in women with poor ovarian response to the patient-oriented strategies encompassing individualized oocyte number (POSEIDON) criteria.

Methods: This cohort study selected 3347 patients with low ovarian response and divided them into four subgroups according to the POSEIDON criteria: Group 1 (n=947), Group 2 (n=778), Group 3 (n=164), and Group 4 (n=1458). Logistic regression analysis was used to evaluate the role of TCM treatment on the CLBR of patients with poor ovarian response to POSEIDON criteria.

The relationship between physical activity and sleep disorders in adolescents: a chain-mediated model of anxiety and mobile phone dependence.

Background: Adolescent sleep disorders have emerged as a significant global public health issue. This study aims to investigate the relationship between physical activity and sleep disorders in adolescents, and to further analyze the chain mediating effects of anxiety and mobile phone dependence, with the goal of providing empirical evidence for related clinical research.

Methods: This cross-sectional study collected data through an offline questionnaire survey conducted in 2024.

Semantic Mask Reconstruction and Category Semantic Learning for few-shot image generation.

Few-shot image generation aims at generating novel images for the unseen category when given K images from the same category. Despite significant advancements in existing few-shot image generation methods, great challenges remain regarding the quality and diversity of the generated images. This issue stems from the model's struggle to fully comprehend the semantic content of images and extract sufficiently semantic representations.

Construction of label-free electrochemical aptasensor and logic circuit based on triple-stranded DNA molecular switch.

Background: Pesticide residues can cause chronic toxicity to the human body and lead to a series of diseases that damage the liver. Therefore, developing a highly sensitive, selective, and low-cost pesticide residues detection method is of great significance for protecting human health and safety. Nowadays, commonly used methods for pesticide residue detection include gas chromatography, high-performance liquid chromatography, and fluorescence sensing.

Decoding the genome of SARS-CoV-2: a pathway to drug development through translation inhibition.

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes the coronavirus disease 2019 (COVID-19) pandemic and is continuously spreading globally. The continuous emergence of new SARS-CoV-2 variants keeps posing threats, highlighting the need for fast-acting, mutation-resistant broad-spectrum therapeutics. Protein translation is vital for SARS-CoV-2 replication, producing early non-structural proteins for RNA replication and transcription, and late structural proteins for virion assembly.

Construction and Application Effect Analysis of Orthopedic Pain Care Ward under Multi-Disciplinary Cooperation Model.

A multidisciplinary team (MDT) approach is a nurse-led pain management method that involves collaboration with staff from other departments. The purpose of this paper was to discuss the construction and application effect of a pain care ward in orthopedics utilizing the MDT approach. A retrospective analysis of case data was conducted, selecting 90 patients with hip joint fractures who underwent hip replacement arthroplasty (HRA) at our hospital between February 2021 and February 2024.

Characteristics and development of steepland gullies in the dry valleys of Southwest China.

In semi-arid and arid areas, gully erosion is one of the most destructive forms of erosion and causes serious land degradation and resource destruction. Steepland gullies are widely distributed in the dry valleys of southwest China, and their formation is one of the main causes of soil erosion and the destruction of sloping farmland in the region. Previous research on the development of steepland gullies is limited, and further study is needed.

Biomimetic Morphogenesis of Strontium Chitosan-Gelatin Composite Aggregates via EPD and Biomineralization in vitro and in vivo.

Introduction: Biomineralization has been increasingly adopted for the synthesis of advanced materials with superior properties. Hierarchical architecture growth mimicking biomineralization has been studied using various organic molecules to template inorganic materials with controlled morphology. In our previous study, self-assembled Sr/CS/G(SrCO-chitosan-gelatin) aggregates were fabricated using electrophoretic deposition (EPD).

Aged hippocampal single-cell atlas screening unveils disrupted neuroglial system in postoperative cognitive impairment.

Glia-neuron interaction is a crucial feature in aged hippocampus during the occurrence of postoperative cognitive impairment. However, the regulatory effects of microglia, astrocytes, and oligodendrocytes in this glia-neuron interaction, the potential mechanisms and gene targets are still to be elucidated. Here, single-cell RNA sequencing was performed to detect the perioperative genomic expression characteristics of neuroglial system in the hippocampus of aged mice, and to investigate the potential cross-cellular mechanisms and valuable treatment options for glia-neuron interaction-related cognitive impairment.

The Enhanced Hydrophobic, Photothermal, and Anti-Icing/Ice-Melting Performance of C/TiN/WC/PDMS Composite Coating by Inserting a Thermal Insulation Layer.

Enhancing the hydrophobic and photothermal characteristics of the coating can significantly boost its anti-icing/ice-melting capabilities. In this study, an epoxy resin thermal insulation layer is interposed between the aluminum sheet substrate and the C/TiN/WC/PDMS photothermal composite coating. This method not only equips the coating with exceptional superhydrophobic properties but also markedly elevates its photothermal and anti-icing/ice-melting performance.

Correlation of Serum Oxidative Stress with the Effect of Initial Induction Chemotherapy in Acute Myeloid Leukemia.

Background: Achieving first complete remission with induction chemotherapy (ICT) for acute myeloid leukemia (AML) correlates with patient's prognosis. This study aimed to determine the correlation between oxidative stress and the outcome of ICT in AML patients.

Methods: A total of 195 AML patients underwent initial ICT at the Longyan First Affiliated Hospital of Fujian Medical University from 06-11-2018 to 12-30-2023.

The interactive effect of extreme weather events and PM on respiratory health among the elderly: a case-crossover study in a high-altitude city.

With climate change posing increasing threats and aging populations, understanding the complex relationship between extreme temperatures, PM pollution, and respiratory health among the elderly is crucial. While some research exists, there remains a significant gap in studying the combined effects of heat waves, cold spells, and PM on elderly respiratory health in high-altitude regions. We collected data from Xining (2016-2021), including respiratory disease outpatient visits, meteorological, and pollutant data.

Deciphering the role of PLCD3 in lung cancer: A gateway to glycolytic reprogramming via PKC-Rap1 activation.

PLCD3 belongs to the phospholipase C delta group and is involved in numerous biological functions, including cell growth, programmed cell death, and specialization. However, the role of PLCD3 in lung cancer still needs further investigation. This research aimed to investigate if PLCD3 influences glycolytic reprogramming and lung cancer development through the PKC-dependent Rap1 signaling pathway.

Proliferation capability of natural killer cells upon cytokines stimulation correlated negatively with serum lactate dehydrogenase level in coronary artery disease patients.

Background: Natural killer (NK) cells are proposed to participate in coronary artery disease (CAD) development. However, little is known about how CAD patients' NK cells respond to different stimulatory factors in terms of proliferation capability.

Methods And Results: Twenty-nine CAD patients' peripheral blood NK cells were isolated and individually treated with IL-2, IL-12, IL-15, IL-18, IL-21, cortisone acetate, hydrocortisone, or ascorbic acid for 36 hours, followed by cell cycle analysis using flow cytometry.

Physical activity moderated the mediating effect of self-control between bullying victimization and mobile phone addiction among college students.

This study aims to investigate the relationship between bullying victimization and mobile phone addiction (MPA) among college students, taking into consideration the mediating role of self-control and the moderating role of physical activity. A self-report survey was administered to college students from 4 universities in Guangxi, Liaoning, and Hunan provinces in China. Participants were asked to report their experiences of bullying victimization, level of MPA, self-control, and physical activity.

Investigating the NH Preintercalation and Surface Coordination Effects on MnO for Ammonium-Ion Supercapacitors.

Ion preintercalation is an effective method for fine-tuning the electrochemical characteristics of electrode materials, thereby enhancing the performance of aqueous ammonium-ion hybrid supercapacitors (A-HSCs). However, much of the current research on ion preintercalation lacks controllability, and the underlying mechanisms remain unclear. In this study, we employ a two-step electrochemical activation approach, involving galvanostatic charge-discharge and cyclic voltammetry, to modulate the preintercalation of NH in MnO.