Publications by authors named "Ting Kun Au-Yong"

Article Synopsis
  • Phyllodes tumor is a rare type of breast tumor that can spread to other parts of the body, mostly the lungs, bones, and liver.
  • A 52-year-old woman had this tumor removed from her breast but later found out it had spread to her lungs and many other organs.
  • Doctors used special scans to discover the new places where the tumor had spread within two years after her surgery.
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Objectives: The study aimed to evaluate the frequency of incidental suspicious lesions detected by flourine-18 fluorodeoxyglucose PET/computed tomography ( 18 F-FDG PET/CT) scans done for staging or restaging in adult cancer patients. We further determined the detection rate of synchronous and metachronous malignancies in these suspicious lesions after further investigations.

Materials And Methods: This retrospective analysis evaluated the consecutive patients with 18 F-FDG PET/CT scans done in Queen Elizabeth Hospital (QEH), Hong Kong between July 2021 and June 2022.

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Article Synopsis
  • The study conducts a systematic review and meta-analysis to evaluate the effectiveness of 18 F-FDG PET imaging in identifying brain metastases arising from various cancers, revealing potential differences in imaging outcomes based on the type of cancer.
  • Among the 2227 patients analyzed from 11 studies, the findings indicated a low sensitivity (44%) but high specificity (99%) of FDG PET for detecting brain metastases, with significant variability in results across studies.
  • The analysis suggests that awareness of asymmetrical hypometabolism could enhance the sensitivity of FDG PET, indicating a need for further research to refine diagnostic techniques.
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Interpretation of FDG PET images in oncology patients is in general a visual exercise of search for focal increased uptake (hypermetabolism). However, in some cases, hypometabolism (focal decreased uptake) can matter as much as hypermetabolism. We report three cases of FDG PET studies for oncological indications.

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This case report illustrates a rare case of dermatopathic lymphadenitis with interval F-fluorodeoxyglucose positron emission tomography/ computed tomography performed. The clinical presentation, imaging, and histological findings are described. We discuss the diagnostic challenges in this case.

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For decades, conventional nuclear medicine techniques have been utilized for the assessment of many infectious and inflammatory diseases. Most of these techniques have limitations such as the relatively low spatial resolution, being time consuming and low sensitivity or specificity. In recent years, FDG-PET/CT has shown promising role in the management of such diseases.

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Article Synopsis
  • The study focuses on identifying factors that impact progression-free survival in patients with metastatic lung adenocarcinoma treated with tyrosine kinase inhibitors (TKIs).
  • Statistical analysis of 41 patients revealed that primary tumor SUV, serum CEA levels, gender, and smoking history are significant prognostic indicators.
  • Specifically, lower SUV and serum CEA levels, being female, and having a history of never smoking suggest a better response to TKI treatment.
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A 72-year-old gentleman underwent myocardial perfusion scintigraphy (MPS) for sinus tachycardia of unknown cause. Baseline electrocardiography (ECG) showed sinus tachycardia and electrical alternans. Thallium-201 stress-redistribution MPS was performed with dipyridamole stress.

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The aim of this retrospective study is to evaluate the clinical impact and efficacy of fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET/CT) on management decisions for patients suffering from clinically operable non-small-cell lung cancer (NSCLC). A retrospective review of 186 potentially operable NSCLC patients who underwent whole-body PET/CT examination in 2012 was performed. The patients were further analyzed via the electronic patient record (ePR) system for relevant findings.

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