Countermeasures and Application Effect of Nursing Interventions in Maintenance Hemodialysis Patients with Complications of Secondary Hyperparathyroidism.

Background: Secondary hyperparathyroidism commonly arises in individuals with end-stage kidney disease, especially those who undergo maintenance hemodialysis (MHD). This study investigated strategies and effectiveness of nursing interventions in MHD patients with secondary hyperparathyroidism complications.

Methodology: This study is a retrospective analysis conducted at the General Hospital of Northern Theater Command.

Electroencephalogram-Based Subject Matching Learning (ESML): A Deep Learning Framework on Electroencephalogram-Based Biometrics and Task Identification.

An EEG signal (Electroencephalogram) is a bioelectric phenomenon reflecting human brain activities. In this paper, we propose a novel deep learning framework ESML (EEG-based Subject Matching Learning) using raw EEG signals to learn latent representations for EEG-based user identification and tack classification. ESML consists of two parts: one is the ESML1 model via an LSTM-based method for EEG-user linking, and one is the ESML2 model via a CNN-based method for EEG-task linking.

Efficacy of modified kidner procedure combined with subtalar arthroereisis treating adolescent type 2 painful accessory navicular with flexible flatfoot.

Purpose: To investigate the clinical efficacy of modified kidner procedure combined with subtalar arthroereisis in the treatment of adolescent type II painful accessory navicular with flexible flatfoot.

Methods: From January 2018 to January 2022, 25 adolescent patients (40 feet) with painful type II accessory navicular and flexible flatfoot admitted to our hospital were enrolled in the study, including 13 males (23 feet) and 12 females (17 feet). All patients underwent modified kidner procedure combined with subtalar joint arthrodesis.

Virtual screening of novel mTOR inhibitors for the potential treatment of human colorectal cancer.

The abnormal activation of the mTOR pathway is closely related to the occurrence and progression of cancer, especially colorectal cancer. In this study, a rational virtual screening strategy has been established and MT-5, a novel mTOR inhibitor with a quinoline scaffold, was obtained from the ChemDiv database. MT-5 showed potent kinase inhibitory activity (IC: 8.

The Treatment Combining Antiangiogenesis with Chemoradiotherapy Impinges on the Peripheral Circulation Vascular Endothelial Cells and Therapeutic Effect in the Patients with Locally Advanced Nasopharyngeal Carcinoma.

This study was implemented for the evaluation on the circulating endothelial cells' (CECs) clinical significance in the locally advanced nasopharyngeal carcinoma treatment with endostatin-combined chemoradiotherapy. This study enrolled 47 patients with locally advanced nasopharyngeal carcinoma who were hospitalized from May 9, 2012 to March 10, 2013. These patients were split up into the observation group (25 patients) and control group (22 patients).

Exosomal microRNA-150-5p from bone marrow mesenchymal stromal cells mitigates cerebral ischemia/reperfusion injury via targeting toll-like receptor 5.

MicroRNA (miR)-150-5p has been investigated in many studies, while the role of exosomal miR-150-5p from bone arrow mesenchymal stromal cells (BMSCs) on cerebral ischemia/reperfusion (I/R) injury is not fully explored. This research aims to probe the effects of exosomal miR-150-5p from BMSCs on cerebral I/R injury via regulating B-cell translocation gene 2 (TLR5). Bone marrow mesenchymal stem cell-derived exosomes (BMSCs-Exo) were isolated and identified.

Dodecahedral Au/Pt Nanobowls as Robust Plasmonic Electrocatalysts for Methanol Oxidation under Visible-Light Illumination.

Plasmonic nanostructures with large absorption areas under resonant excitation have been utilized extensively in photon-assisted applications. In this work, dodecahedral Au nanobowls were first prepared by an easy and template-free method only through the introduction of H PtCl and I during the growth procedure. The Au nanobowls show electron-field enhancement due to the high curvature of the bowl edge, the open region, and dodecahedral morphology.

BaTiO assisted PAN fiber preparation of high performance flexible nanogenerator.

Recently, polyacrylonitrile (PAN) fiber films have shown greater advantages over polyvinylidene fluoride (PVDF) in the field of energy harvesting. Adding other substances with high piezoelectric coefficient is worth exploring to further improve the output voltage of PAN. Here, we successfully dispersed high dielectric constant barium titanate in PAN nanofiber films with different dosages using an electrospinning technology.

High-Density Pd Nanorod Arrays on Au Nanocrystals for High-Performance Ethanol Electrooxidation.

In the synthesis of Au/Pd bimetallic nanocrystals, a layer-by-layer growth is favored, owing to the low bonding energy between Pd atoms ( E) in comparison with E, resulting in homogeneous core/shell nanostructures. Herein, we demonstrate designed synthetic tactics to unconventional Au/Pd heterostructures through a deposition-dominant growth pathway of the newly reduced Pd atoms, which break the intrinsically favored layer-by-layer growth. Pd thus grows on Au seeds in a heterogeneous nucleation manner.

AuPt Bipyramid Nanoframes as Multifunctional Platforms for In Situ Monitoring of the Reduction of Nitrobenzene and Enhanced Electrocatalytic Methanol Oxidation.

Multifunctional metal nanostructures with a hollow feature, especially for nanoframes, are highly attractive owing to their high surface-to-volume ratios. However, pre-grown metal nanocrystals are always involved during the preparation procedure, and a synthetic strategy without the use of a pre-grown template is still a challenge. In this article, a template-free strategy is reported for the preparation of novel AuPt alloy nanoframes through simply mixing HAuCl and H PtCl under mild conditions.

[Phase II clinical trial of two different modes of administration of the induction chemotherapy for locally advanced nasopharyngeal carcinoma].

Objective: To compare the therapeutic effects, toxic side effects and influence on the immune function in patients treated with TPF [docetaxel (DOC) + cisplatin (DDP) + 5-fluorouracil (5-Fu)] induction chronochemotherapy and conventional chemotherapy for locally advanced nasopharyngeal (NPC).

Methods: Seventy patients with locally advanced nasopharyngeal carcinoma were treated in our department at their first visit from April 2013 to December 2013. They were divided randomly into two groups: the chronochemotherapy group (38 patients) and conventional chemotherapy group (32 patients).

[Clinical results of recombinant human endostatin combined with chemoradiotherapy for locally advanced nasopharyngeal carcinoma].

Objective: To compare the short-term efficacy and observe the tolerability and safety of recombinant human endostatin combined with induction chemotherapy followed by chemoradiotherapy for locally advanced nasopharyngeal carcinoma.

Methods: Fifty-three patients with locally advanced nasopharyngeal carcinoma, who received recombinant human endostatin combined with induction chemotherapy followed by chemoradiotherapy, treated in our department from December 2011 to March 2013 were included in the study group of this study. Another 48 patients, who received induction chemotherapy followed by chemoradiotherapy alone in the same period, were chosen as a control group.

Expressions of CD147, MMP-2 and MMP-9 in laryngeal carcinoma and its correlation with poor prognosis.

The objectives of this study are to investigate the expressions of matrix metalloproteinase inducing factor (CD147), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9) in laryngeal tumor tissues and its significant correlation with tumor infiltration, metastasis and prognosis. Laryngeal tumor tissue from 48 laryngeal cancer patients with complete clinical information was collected. The laryngitis tissue from 15 patients were collected as control group.

Blocking the butyrate-formation pathway impairs hydrogen production in Clostridium perfringens.

Inactivating competitive pathways will improve fermentative hydrogen production by obligate anaerobes, such as those of genus Clostridium. In our previous study, the hydrogen yield of Clostridium perfringens W13 in which l-lactate dehydrogenase was inactivated increased by 44% when compared with its original strain W12. In this study, we explored whether blocking butyrate formation pathway would increase hydrogen yield.

Characterization of the plasma membrane proteins and receptor-like kinases associated with secondary vascular differentiation in poplar.

The constituents of plasma membrane proteins, particularly the integral membrane proteins, are closely associated with the differentiation of plant cells. Secondary vascular differentiation, which gives rise to the increase in plant stem diameter, is the key process by which the volume of the plant body grows. However, little is known about the plasma membrane proteins that specifically function in the vascular differentiation process.

Proteomic study of Carissa spinarum in response to combined heat and drought stress.

Carissa spinarum is one of the secondary advantage plants grown in dry-hot valleys in China, which can survive under stress conditions of high temperature and extreme low humidity. Here, we studied the physiological and proteomic changes of C. spinarum in response to 42 degrees C heat stress treatment in combination with drought stress.