Publications by authors named "Tine Lorentzen"
Background: The increased use of neoadjuvant chemotherapy (NACT) facilitates an increase in breast-conserving surgery and immediate breast reconstruction. While NACT is considered to have the same oncological safety as adjuvant chemotherapy, evidence on the impact of NACT on surgical outcomes following breast surgery is unclear and varies across studies. The aim of this systematic review and meta-analysis was to assess the impact of NACT on surgical complications in breast cancer patients undergoing any kind of breast surgery.
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- Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious drug reactions that can lead to high mortality rates, and there’s no agreed-upon treatment plan across Europe.
- * A retrospective study involving 212 adults aimed to identify treatment methods, risk factors, and outcomes for patients with SJS/TEN in 13 centers from 2015 to 2019, revealing that most patients had identified culprit drugs, primarily antibiotics and anticonvulsants.
- * The findings showed that 63.7% of patients experienced severe complications, with a 20.8% mortality rate within 6 weeks, and significant body surface area detachment was linked to more severe outcomes.
Neurofibromatosis type 1 (NF1) is a genetic disorder affecting the skin, nervous system, eyes and bones. Pulmonary involvement is unknown to many physicians. Yet, patients may be affected by lung bullae and cysts, which represent an increased risk for secondary spontaneous pneumothorax (SSP).
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