Publications by authors named "Tina Yao"
Article Synopsis
- The study addresses the challenge of accurately identifying and measuring aortic aneurysms, which is crucial but often limited by the time-consuming nature of high-resolution 3D CMR sequences used for assessment.
- Researchers developed a 3D U-Net that can create detailed 3D segmentations of the aorta from standard 2D images with lower resolution, enhancing the efficiency of aortic assessments in clinical and population studies.
- The results showed that the new U-Net model produced 93% clinically suitable segmentations and achieved a high DICE score of 0.9, matching the accuracy of traditional high-resolution methods, indicating its potential for reliable clinical use.
Computational fluid dynamics (CFD) can be used for non-invasive evaluation of hemodynamics. However, its routine use is limited by labor-intensive manual segmentation, CFD mesh creation, and time-consuming simulation. This study aims to train a deep learning model to both generate patient-specific volume-meshes of the pulmonary artery from 3D cardiac MRI data and directly estimate CFD flow fields.
View Article and Find Full Text PDFPurpose To develop an end-to-end deep learning (DL) pipeline for automated ventricular segmentation of cardiac MRI data from a multicenter registry of patients with Fontan circulation (Fontan Outcomes Registry Using CMR Examinations [FORCE]). Materials and Methods This retrospective study used 250 cardiac MRI examinations (November 2007-December 2022) from 13 institutions for training, validation, and testing. The pipeline contained three DL models: a classifier to identify short-axis cine stacks and two U-Net 3+ models for image cropping and segmentation.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the process of cell division in archaea, highlighting how mechanical forces from cytoskeletal polymers drive this physical process.
- A new model was developed that suggests archaea use a unique division mechanism involving changes in the curvature of cytoskeletal filaments, which help constrict the cell membrane during division.
- The findings indicate that this mechanism of cytokinesis could apply broadly across life forms, providing insights into fundamental biological processes beyond just archaea.