Publications by authors named "Timothy Richard Stowe"
Article Synopsis
- The primary cilium is a key organelle involved in sensory functions and signaling, and issues in its formation can lead to genetic disorders called ciliopathies.
- The study reveals that autophagy, a cellular degradation process, is essential for removing the ciliopathy protein OFD1 from centriolar satellites, facilitating the formation of primary cilia.
- By manipulating OFD1 levels, researchers found that enhancing or reducing its presence can significantly influence cilia development in normal and cancer cells, highlighting autophagy's important role in the biogenesis of organelles.
