A primary cardiac sarcoma presenting with superior vena cava obstruction.

Superior vena cava (SVC) obstruction leads to a constellation of symptoms and signs that encompass the SVC syndrome. Today, malignancy accounts for 65% of all cases. The most common neoplastic causes are non–small cell lung cancer (50%), small cell lung cancer (25%), lymphoma, and metastasis.

Admixture of ephedrine to offset side effects of propofol: a randomized, controlled trial.

Study Objective: To determine whether adding ephedrine to propofol is as effective as adding lidocaine at reducing injection pain, and its effects on hemodynamics.

Design: Randomized, double-blinded, controlled trial.

Setting: District general hospital in the United Kingdom.

Hypotension and ST depression as a result of disulfiram ethanol reaction.

A case report of a 27-year-old man who developed significant hypotension and ischaemic ECG changes as a result of a disulfiram ethanol reaction. He was treated with intravenous fluids and norepinephrine, which has been advocated as the pressor agent of choice. This case highlights the potential dangers of disulfiram, a drug that can be beneficial in the short term, but not proven to improve long-term outcome in the treatment of alcoholism.

Scottish urban versus rural trauma outcome study.

Background: Outcome following trauma and health care access are important components of health care planning. Resources are limited and quality information is required. We set the objective of comparing the outcomes for patients suffering significant trauma in urban and rural environments in Scotland.

Effect of patients' age on management of acute intracranial haematoma: prospective national study.

Objective: To determine whether the management of head injuries differs between patients aged > or =65 years and those <65.

Design: Prospective observational national study over four years.

Setting: 25 Scottish hospitals that admit trauma patients.

The Drosophila STAT protein, stat92E, regulates follicle cell differentiation during oogenesis.

Signal transducer and activator of transcription (STAT) proteins are transcription factors that play a critical role in the response of a variety of eukaryotic cells to cytokine and growth factor signaling. In Drosophila, the STAT homolog encoded by the stat92E gene is required for the normal development of multiple tissues, including embryonic segmentation, imaginal discs, blood cells, male germ cells, and sex determination. We used multiple approaches to study the role of stat92E in oogenesis.