Publications by authors named "Timothy Lawrence"

The current study explores whether expressing feelings about violence through journal or notebook and/or school assignment might be associated with a decrease in delinquent activities, such as substance use, theft of property, and assaultive behaviors. A cross-sectional study with purposive sampling was conducted. The participants were comprised of African American adolescents in four Chicago's Southside neighborhoods.

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Dating violence is often perpetrated among adolescents, which increases the efforts to better understand individual risk factors for preventive efforts. Although multiple forms (i.e.

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Background: Prior studies have shown that marijuana use is often associated with physical teen dating violence. However, few studies have examined the longitudinal mediating effects of associating with antisocial peers and impulsivity on this relationship. Also, few studies have estimated the cascading developmental impact of marijuana use and antisocial peer association, predicting the continued marijuana use and antisocial peer associations while considering the risk of impulsivity in physical teen dating violence.

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Parole boards are often required to make many release recommendations after reviewing a substantial amount of information in a short timeframe. While making release decisions, parole board members might be motivated to sacrifice accuracy and, instead, use heuristics, such as their emotions. Emotions might increase the reliance on risk or threat related information, such as an inmate's mental illness status.

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Purpose: Sibling aggression has been recognized as a common form of family violence. However, further research is needed to elucidate several antecedents of sibling aggression perpetration and bullying victimization, such as substance use and depressive symptoms. Also, more studies are needed to identify the mediating pathways of depressive symptoms and substance use, which could explain the association between bullying victimization and sibling aggression perpetration as well as the association between sibling aggression victimization and bullying victimization, controlling for exposure to family violence and demographic variables.

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Ample evidence exists suggesting that exposure to family violence leads to substance use and this relationship is moderated by gender; however, much is still unknown of the underlying mechanism of this relationship. Thus, the current study first examined whether exposure to family violence was associated with substance use. Then consistent with the self-medication hypothesis, we tested whether depressive symptoms mediated the relations between exposure to family violence and substance use.

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Article Synopsis
  • The study examines the diversity of bacteria in the atmospheric boundary layer across twelve different global locations, identifying how various biomes influence this diversity.
  • It finds that atmospheric bacterial diversity negatively correlates with mean annual precipitation, while it positively correlates with mean annual temperature, and highlights unique community structures for both atmosphere and soil at each site.
  • The research emphasizes that local soils play a more significant role than distant soils in shaping atmospheric diversity, especially in semi-arid and arid regions, underscoring the complex interactions in atmospheric microbiota and their impact on ecosystems.
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Background: The developmental trauma theory suggests that traumatic events impede the ability of individuals to form interpersonal relationships, impair cognition, affect, and increase the vulnerability of adolescents to develop psychopathology. However, few studies have examined the applicability of this theory among African American adolescents who were exposed to community violence and adverse outcomes, including bullying victimization and somatic symptoms.

Aims: Therefore, the purpose of the present study is to first test the association between exposure to community violence and somatic symptoms.

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Female offenders released from prison often face challenges within the community such as lack of employment, inconsistent attendance in substance use treatment, and complying with parole and probation conditions, which typically decreases their self-efficacy and motivation to refrain from reoffending. Despite this, much is still unknown of psychological factors that could impact female offenders' attitudes toward self-efficacy, such as mental illness symptoms, Adverse Childhood Experiences (ACEs), and personality differences. Thus, this cross-sectional study explored whether mental illness symptoms, ACEs, and personality differences were associated with attitudes toward self-efficacy ( = 398).

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Youth victimization in schools remains a fervent public health issue, despite increased awareness of this issue, and this is especially true for marginalized populations like lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth. Youth violence has been studied widely, but less research has sought to understand factors protective of violence victimization, particularly protective factors shared across multiple forms of violence. In the current study, we utilized latent class analysis to test patterns of three types of victimization: peer victimization (PV), homophobic name-calling victimization (HNCV), and sexual harassment victimization (SHV).

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The present study examined whether cyberbullying, relational victimization, and family support were associated with depressive symptoms and substance use among adolescents ( = 1232). A path analysis revealed that cyberbullying, relational victimization, and family support were positively associated with depressive symptoms. Also, cyberbullying and relational victimization was positively related to substance use, whereas family support was not statistically predictive of substance use.

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The present study examined whether parental criticism, active coping, and peer support associated with depressive symptoms. Then using two mediation models, this study explored whether parental criticism related to depressive symptoms through active coping while controlling for peer support among African American Adolescents (N = 883). Results from a multiple regression analysis revealed that maternal and paternal criticism positively associated with depressive symptoms in contrast to active coping and peer support.

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Given the increase of depressive symptoms among adolescents, it is essential to investigate familial and temperamental correlates of depressive symptoms such as parental support, marital conflict, and stress. Thus, using a cross-sectional design, the current study examined whether parental support, marital conflict, and stress predicted depressive symptoms. Then, using structural equation modeling, this study tested whether stress mediated the relationships among parental support, marital conflict, and depressive symptoms among African American adolescents while controlling for sex ( = 883).

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Parole boards often incorporate numerous factors when making release decisions. These factors are typically related to the inmates' case files. However, in some instances, parole boards' decisions are influenced by factors outside of the case files, sometimes referred to as extra-legal factors.

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In the current study, the actor-observer effect is tested with both mock parole board members and the public evaluating the responsibility of parole board members for a decision resulting in a parolee reoffending and committing a murder. Participants (two samples with a combined  = 1317) were randomly assigned to act as a mock parole board member and make a decision (which ended in the parolee reoffending) or as a member of the public who read a story about the same parole decision and outcome. Findings suggest that the traditional actor-observer asymmetry emerged across blame and responsibility concepts, emotion and moral judgments.

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Converging evidence suggests that the activation of the inflammatory cytokine pathway is important in the pathophysiology of unipolar depression. Antidepressants have anti-inflammatory properties and evidence suggests that inter-individual variability in response to antidepressants may reflect genetic differences in the inflammatory cytokine pathway. In particular, protein levels of Tumor Necrosis Factor (TNF) and the SNPs rs1126757 in interleukin-11 (IL11), and rs7801617 in interleukin-6 (IL6), have previously been implicated in the clinical response to the selective serotonin reuptake inhibitor (SSRI) antidepressant escitalopram.

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Objective: To review the sparse literature that exists on the topic of head injury assessment and management outside high-income settings and attempt to: 1) identify strengths and weaknesses of the currently published clinical data relating to head injuries in lower-income countries; and 2) consider specific objectives for future head injury research in the resource-limited setting. If levels of excellence in neurosurgery are to be sustainably achieved outside high-income countries, there must be good systems of research and audit in place both to identify where development is needed and to evaluate the efficacy of development projects already in progress.

Methods: We performed a MEDLINE search of publications between 1980 and 2010 by using the search terms head injuries/craniocerebral trauma/neurotrauma and developing world/developing nations.

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We describe the process of establishing a large database for the investigation of craniotomy infection and the preliminary results of this database. The initial results have been used to generate a cost analysis for craniotomy infection. The craniotomy infections database prospectively registers craniotomy cases taking place in the John Radcliffe Hospital.

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We have shown that neuropeptide Y (NPY), a peptide neurotransmitter released by hippocampal interneurons, is proliferative for hippocampal neural stem progenitor cells (NSPCs) via the Y1 receptor. Fibroblast growth factor (FGF) 2, released predominantly by astrocytes, is also a powerful mitogen for postnatal and adult NSPCs, via the FGFR1 receptor. Knockout studies show that NPY and FGF2 are individually necessary, but not sufficient, for seizure-induced neurogenesis, suggesting a possible interaction.

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Molecular markers associated with gene coding regions are useful tools for bridging functional and structural genomics. Due to their high abundance in plant genomes, single nucleotide polymorphisms (SNPs) are present within virtually all genomic regions, including most coding sequences. The objective of this study was to develop a set of SNPs for the apple by taking advantage of the wealth of genomics resources available for the apple, including a large collection of expressed sequenced tags (ESTs).

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APB (DL-2-amino-4-phosphonobutyric acid) has been found to affect the retinal processing of many vertebrate species as evidenced by the suppression of the b-wave component of the electroretinogram (ERG). The present study examined the effects of APB on the cone contributions to the ERG response of adult zebrafish (Danio rerio). ERG responses were obtained from light-adapted adult zebrafish following intravitreal injection of either saline alone or saline with various concentrations of APB ranging from 10 microm to 500 microM.

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