Publications by authors named "Timothy L Brennan"

Article Synopsis
  • - Bronchiolitis obliterans syndrome (BOS) is a serious lung condition that can develop after receiving a stem cell transplant, and this study tested the effectiveness of ruxolitinib in treating it.
  • - The trial involved 49 adult participants divided into two groups based on how recently they were diagnosed with BOS; results showed that 27.8% of newly diagnosed patients improved, while 92.3% of those with established BOS maintained stable lung function after treatment.
  • - Overall, ruxolitinib had a lung-specific response rate of 34.7% among all participants with most positive outcomes seen in patients with mild to moderate disease, indicating it could be a beneficial treatment option for BOS
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