Reduced estimated glomerular filtration rate (eGFR <60 mL/min/1.73 m ) at first transurethral resection of bladder tumour is a significant predictor of subsequent recurrence and progression.

Objective: To evaluate if moderate chronic kidney disease [CKD; estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m ] is associated with high rates of non-muscle-invasive bladder cancer (NMIBC) recurrence or progression.

Patients And Methods: A multi-institutional database identified patients with serum creatinine values prior to first transurethral resection of bladder tumour (TURBT).

Renin-Angiotensin Inhibitors Decrease Recurrence after Transurethral Resection of Bladder Tumor in Patients with Nonmuscle Invasive Bladder Cancer.

Purpose: Prior reports suggest that renin-angiotensin system inhibition may decrease nonmuscle invasive bladder cancer recurrence. We evaluated whether angiotensin converting enzyme inhibitor or angiotensin receptor blocker treatment at initial surgery was associated with decreased recurrence or progression in patients with nonmuscle invasive bladder cancer.

Materials And Methods: Using an institutional bladder cancer database we identified 340 patients with data available on initial transurethral resection of bladder tumor.