Publications by authors named "Timothy J Humlicek"

Article Synopsis
  • * A retrospective study analyzed data from 42 pediatric patients treated with either bivalirudin or UFH between 2016-2020, focusing on outcomes related to bleeding and thrombotic complications.
  • * Results indicated that bivalirudin is associated with significantly lower rates of major bleeding complications compared to UFH, while rates of major thrombotic events did not significantly differ between the two anticoagulants.
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Objectives: Determine the pharmacokinetic disposition of vancomycin in the pediatric ventricular assist device population.

Design: A retrospective, population pharmacokinetic study.

Setting: Large, quaternary care children's hospital.

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The prevalence and characteristics of anemia and iron deficiency in children supported by a ventricular assist device (VAD) are unknown. Patients <21 years of age on durable VAD support for ≥7 days at Texas Children's Hospital from 2006 to 2015 were retrospectively reviewed. Red blood cell (RBC) and iron deficiency indices in pulsatile VAD (P-VAD) and continuous-flow VAD (CF-VAD) were evaluated.

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Hyponatremia is a common finding in adults hospitalized with heart failure (HF) and is associated with longer hospital stays and increased mortality. The significance of hyponatremia in children with HF is not known. We sought to determine the incidence of hyponatremia and association with clinical outcome in children hospitalized with HF.

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Objective: To assess the frequency of inpatient 30-day readmission for heart failure in children with cardiomyopathy discharged after an admission for heart failure and the impact of discharge pharmacotherapy on readmissions.

Study Design: The Pediatric Health Information System Database was queried for patients ≤18 years of age with an International Classification of Diseases, Ninth Revision code for heart failure (428.xx) or cardiomyopathy (425.

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