Age-Related Features of the Function of the Hypothalamic-Pituitary-Thyroid (HPT) Axis in Nonhuman Primates under Constant Lighting.

We studied the features of the functioning of the hypothalamic-pituitary-thyroid (HPT) axis under conditions of constant (4 weeks) lighting (LED lamps intended for office and residential premise) on a translational model of young adult and old female rhesus monkeys, in particular taking into account their behavior. Constant lightning had no significant effect on the levels of thyroid-stimulating hormone, thyroxine, and triiodothyronine under basal conditions in all animals, regardless of age and behavioral characteristics, but induced a decrease in thyroid function under conditions of its activation with thyrotropin-releasing hormone, mainly in old animals.

Individual Features of the Hypothalamic-Pituitary-Thyroid Axis Functioning during Aging in Non-Human Primates.

Individual features of age-related changes in the function of the neuroendocrine systems are an important problem as the basic component of a personalized approach to predicting and treating age-related pathologies. We studied the age-related features of the function of the hypothalamic-pituitary-thyroid axis in laboratory primates with depression- and anxiety-like behavior (DAB). It was found that in young female rhesus monkeys with DAB, the basal and thyrotropin-releasing hormone-stimulated levels of thyroid-stimulating hormone were significantly lower than in young animals with standard behavior (control).

EXERIENCE IN PREVENTING THE CONSEQUENCES OF MALARIA IMPORTATION IN THE METROPOLIS OF MOSCOW, RUSSIA.

The main purpose of the epidemiological surveillance system for malaria in the Russian Federation is now to prevent the possible consequences of malaria-imported by Russians and foreigners from endemic areas. A quarter of the approximately 100 cases notified each year in the country are detected in Moscow. During an epidemic season, a package of measures to identify infection sources (malaria patients and parasite carriers) and to decline the number of malaria vectors is implemented and the sanitary state, of open water bodies and the efficiency of larvicidal measures are supervised.

Fine mechanisms of the interaction of silver nanoparticles with the cells of Salmonella typhimurium and Staphylococcus aureus.

Silver nanoparticles possess antibacterial effect for various bacteria; however mechanisms of the interaction between Ag-NPs and bacterial cells remain unclear. The aim of our study was to obtain direct evidence of Ag-NPs penetration into cells of Gram-negative bacterium S. typhimurium and Gram-positive bacterium S.

[Dirofilariasis in the Moscow Region, a low disease transmission risk area].

The spread of canine and human dirofilariasis was first studied in the Moscow Region, a low disease transmission risk area. D.repens infestation was found to have a tendency to increase in Moscow residents with the imported cases being predominant.

[Supervision of the sanitary-helminthological state of soil in the inhabited areas of Moscow].

In accordance with the normative and methodical documents [3-5, 7-9], a complex of organizational, sanitary, and antiepidemic actions is performed to protect soil from causative agents of parasitic diseases in Moscow. About 2000 soil samples are annually taken from the playgrounds of children's educational establishments and apartment houses and tested. The soil contamination averages 3.

[Malaria in Moscow (2006-2007): monitoring of the situation and assessment of antimalaria measures].

The malaria situation in Moscow in 2007 versus 2006 improved--the cases of malaria reduced by 16.3%. A total of 30 new cases of malaria were notified (46 cases in 2006), of them there were 34 imported cases and 4 secondary cases to imported ones.

[Malaria in Moscow in 2000-2004].

Malaria was eradicated on the territory of Moscow in 1960; its imported cases mainly from the countries of Asia and Africa and sporadic cases secondary to the imported ones were recorded during the following 40 years. Mass migration of the population (businessmen, seasonal workers, etc.) from the endemic CIS countries in the late 1990s, particularly to the Moscow Region, increased cases of tertian malaria, resulting from the transmission of the infection by the mosquitoes Anopheles.

[Clinical evaluation of the usage of iodine-containing food products in the diet of children].

On the basis of clinical supervision came to a conclusion, that the canned food meat of chickens with sea cabbage can be recommended for use in a dietotherapy of children 1.5-3.5 years with deficiency iodine by a condition.

[New approaches to the eradication of enterobiasis in children].

The paper outlines the results of studies dealt with the detection of risk factors and groups for enterobiasis, the efficiency of the treatment of children suffering from the disease with medamine, biologicals, and Normase. It is shown that risk factors may include an abnormal course of antenatality, minor developmental malformations (diastema, dystrophy, abnormalities of the eye, hand, foot, etc.), as well as early artificial feeding of babies (before they reach 3 months of life).

[Kidney involvement in trophoblastic disease (chorionepithelioma)].

Renal involvement in chorionepithelioma is attributed to tumor destruction and metastases to the kidneys. A rare case of secondary paraneoplastic nephropathy manifesting as nephrotic syndrome in the presence of renal metastases is described. Metastatic lesion of the lungs provoked spontaneous pneumothorax.