Gold Nanoparticles Permit In Situ Absorbed Dose Evaluation in Boron Neutron Capture Therapy for Malignant Tumors.

Boron neutron capture therapy (BNCT) is an anticancer modality realized through B accumulation in tumor cells, neutron irradiation of the tumor, and decay of boron atoms with the release of alpha-particles and lithium nuclei that damage tumor cell DNA. As high-LET particle release takes place inside tumor cells absorbed dose calculations are difficult, since no essential extracellular energy is emitted. We placed gold nanoparticles inside tumor cells saturated with boron to more accurately measure the absorbed dose.

The Measurement of the Neutron Yield of the Li(p,n)Be Reaction in Lithium Targets.

A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The neutron flux is generated as a result of the Li(p,n)Be threshold reaction using the solid lithium target.

Measurement of the Li(p,p'γ)Li reaction cross-section and 478 keV photon yield from a thick lithium target at proton energies from 0.7 to 1.85 MeV.

The Li (p,p'γ)Li reaction cross section and photon yield from a thick lithium target at proton energies from 0.7 to 1.85 MeV have been measured with a HPGe gamma-ray spectrometer.

Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target.

A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.