Herzschrittmacherther Elektrophysiol
September 2022
We present a rare reversible cause of bradycardia. A 49-year-old man who suffered from syncope was administered to our emergency department. In preclinical ECG recordings, a sinus node arrest was documented.
View Article and Find Full Text PDFBackground: Fabry patients on reduced dose of agalsidase-beta or after switch to agalsidase-alfa show a decline in estimated glomerular filtration rate (eGFR) and an increase of the Mainz Severity Score Index.
Methods: In this prospective observational study, we assessed end-organ damage and clinical symptoms in 112 patients who had received agalsidase-beta (1.0 mg/kg) for >1 year, who were (i) non-randomly assigned to continue this treatment regime (regular-dose group, n = 37); (ii) received a reduced dose of agalsidase-beta and subsequent switch to agalsidase-alfa (0.