Publications by authors named "Tim Scorrer"
Article Synopsis
- The study aimed to compare the immune responses of preterm infants receiving a meningococcal B vaccine using either a 2+1 or a 3+1 vaccination schedule while also evaluating the side effects of routine vaccinations.
- The research was conducted in an open-label, phase IV study format across six hospitals in the UK, enrolling 129 preterm infants born before 35 weeks gestation.
- Results indicated that while both vaccination schedules were effective, the 3+1 schedule led to a significantly higher antibody response against a specific strain compared to the 2+1 schedule, but also resulted in more fever episodes after vaccination.
Objective: To describe breastfeeding prevalence and maternal experience in infants with trisomy 21.
Design: Longitudinal cohort study.
Setting: Participants from UK recruited through websites, social media and local collaborators: neonatologists, community paediatricians and research nurses.
Background And Objective: Premature infants have a higher risk of invasive pneumococcal disease and are more likely to have lower vaccine responses compared with term infants. Increasingly, immunization schedules are including a reduced, 2-dose, pneumococcal conjugate vaccine priming schedule. Our goal was to assess the immunogenicity of 3 commonly used 13-valent pneumococcal conjugate vaccine (PCV13) priming schedules in premature infants and their response to a 12-month booster dose.
View Article and Find Full Text PDFLymphocyte subpopulations in premature infants: an observational study.
Arch Dis Child Fetal Neonatal Ed
November 2016
Background And Objectives: The infant's immune system evolves over the first months and years of life. Strong correlation exists between lymphocyte count, lymphocyte subpopulations and gestational age at birth. Associations with antenatal and postnatal steroid treatment, infection and chronic lung disease have also been described.
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