Efficacy and safety of a novel mucoadhesive clobetasol patch for treatment of erosive oral lichen planus: A phase 2 randomized clinical trial.

Background: Oral lichen planus (OLP) is a chronic inflammatory disorder of the oral mucosa. Currently there is no approved treatment for OLP. We report on the efficacy and safety of a novel mucoadhesive clobetasol patch (Rivelin -CLO) for the treatment of OLP.

Granulomatosis with polyangiitis mistaken as a temporomandibular joint disorder: A case report.

Introduction: Granulomatosis with polyangiitis (GPA), is a rare systemic disease that if left untreated, it may lead to death within 6-12 months. This case report describes a 15-year-old female with a 14-month history of epiphora, nasal breathing difficulties, headaches, and jaw pain. The patient reported having various medical procedures attempted to address her symptoms.

A retrospective analysis of referral patterns to a university oral medicine clinic.

Objectives: The aim of this study was to analyze referral patterns to a university-based oral medicine (OM) clinic and to identify access issues to OM care.

Study Design: A retrospective patient chart review on all OM specialists at the University of Alberta (Edmonton, Alberta, Canada) over a 1-year period was performed. Data collected included patient age and gender, referring clinician training and experience, reason and urgency of referral, provisional and final diagnosis, and the referral times.

Eosinophils in human oral squamous carcinoma; role of prostaglandin D2.

Eosinophils are often predominant inflammatory leukocytes infiltrating oral squamous carcinoma (OSC) sites. Prostaglandins are secreted by oral carcinomas and may be involved in eosinophil infiltration. The objective of this study was to determine the factors contributing to eosinophil migration and potential anti-neoplastic effects on OSC.

Submandibular gland transfer for prevention of xerostomia after radiation therapy: swallowing outcomes.

Objective: To assess swallowing outcomes in patients with oropharyngeal carcinoma in relation to the Seikaly-Jha procedure for submandibular gland transfer (SJP). The SJP has recently been described as beneficial in the prevention of xerostomia induced by radiation therapy in patients with head and neck cancer.

Design: Inception cohort.

Periodontal disease and preterm delivery of low-birth-weight infants.

Preterm delivery of low-birth-weight infants (PLBW) remains a significant public health issue and a leading cause of neonatal death and long-term neurodevelopmental disturbances and health problems. Recent epidemiological and microbiological immunological studies have suggested that periodontal disease may be an independent risk factor for PLBW. Postulated mechanisms include translocation of periodontal pathogens to the fetoplacental unit and action of a periodontal reservoir of lipopolysaccharides or inflammatory mediators.