The outcome of treatment in differentiated thyroid cancer according to recommendations in current Dutch and American guidelines.

Objective: Assessment of treatment outcome in current de-escalation for differentiated thyroid cancer (DTC) according to the 2015 Dutch thyroid cancer guidelines (NL-15) and American Thyroid Association guidelines (ATA-15).

Design: Retrospectively, the recommendations of the NL-15 and ATA-15 guidelines were evaluated to estimate potentially adequate, under- and overtreatment of DTC in patients treated in the University Medical Center Groningen between 2007 and 2017.

Patients: A total of 240 patients with a cT1-T3aN0-1aM0 DTC fulfilled the inclusion criteria.