Publications by authors named "Tim Julian Hartung"
The T1-weighted/T2-weighted ratio as a biomarker of anti-NMDA receptor encephalitis.
J Neurol Neurosurg Psychiatry
March 2024
Article Synopsis
- Anti-NMDAR encephalitis shows minimal visible lesions on standard MRIs, but advanced imaging reveals significant white matter damage; the study explores the use of T1-weighted/T2-weighted (T1w/T2w) ratios to assess white matter integrity and its link to cognitive issues.
- In a study of 53 patients and 53 healthy controls, patients displayed lower T1w/T2w ratios in normal appearing white matter, especially linked to reduced verbal memory performance, indicating a correlation between white matter health and cognitive abilities.
- The findings suggest that T1w/T2w ratios effectively identify microstructural brain changes in NMDAR encephalitis patients, potentially serving as a useful imaging outcome measure for