Publications by authors named "Tim J Harries"

Article Synopsis
  • The study used Monte Carlo simulations to explore Raman signals in tissue phantoms and validated the arctk code for replicating experimental results.
  • The experiment involved using Intralipid as a scattering agent in a quartz tank, with a PTFE layer acting as the Raman signal source to observe variations in signal strength based on optical properties and spatial location.
  • Findings indicated that linear extrapolation of scattering coefficients is inaccurate at lower concentrations, contributing vital insights for future noninvasive cancer screening techniques.
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Young stars are surrounded by a circumstellar disk of gas and dust, within which planet formation can occur. Gravitational forces in multiple star systems can disrupt the disk. Theoretical models predict that if the disk is misaligned with the orbital plane of the stars, the disk should warp and break into precessing rings, a phenomenon known as disk tearing.

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Article Synopsis
  • Photothermal therapy with nanoparticles offers a new way to treat cancer by generating heat through light interaction, but it faces challenges for clinical use.
  • Researchers utilized Monte Carlo simulations to better understand how heat is distributed in tumor and surrounding normal tissue, enhancing the current knowledge of thermal dose characterization.
  • Their findings, validated against experimental data, demonstrate that computer simulations can effectively assess the impact of heat on cell survival in both tumors and healthy tissue.
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Deuterium-to-hydrogen (D/H) enrichments in molecular species provide clues about their original formation environment. The organic materials in primitive solar system bodies generally have higher D/H ratios and show greater D/H variation when compared to D/H in solar system water. We propose this difference arises at least in part due to (1) the availability of additional chemical fractionation pathways for organics beyond that for water, and (2) the higher volatility of key carbon reservoirs compared to oxygen.

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Identifying the source of Earth's water is central to understanding the origins of life-fostering environments and to assessing the prevalence of such environments in space. Water throughout the solar system exhibits deuterium-to-hydrogen enrichments, a fossil relic of low-temperature, ion-derived chemistry within either (i) the parent molecular cloud or (ii) the solar nebula protoplanetary disk. Using a comprehensive treatment of disk ionization, we find that ion-driven deuterium pathways are inefficient, which curtails the disk's deuterated water formation and its viability as the sole source for the solar system's water.

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