Publications by authors named "Tim Haydon"
Background And Aims: Prone positioning is commonly applied to improve gas exchange in mechanically ventilated patients with coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS). Whilst prone positioning is effective, specific complications may arise. We aimed to assess the prevalence of specific complications related to prone positioning in patients mechanically ventilated for COVID-19-related ARDS.
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- Neuromuscular blockers (NMBs) are used during prone positioning to improve breathing in patients with COVID-19 related ARDS, but their effects on oxygen levels are unclear.
- A study of 220 adult patients found that those using NMBs experienced significantly higher oxygenation levels (measured by P/F ratios) during prone positioning and even after returning to a supine position compared to those not using NMBs.
- The results indicate that NMBs may enhance oxygenation in COVID-19 ARDS patients during prone positioning, which could influence treatment decisions.
Article Synopsis
- Prone positioning may enhance oxygen levels in patients with acute hypoxemic respiratory failure, especially those with COVID-19, but its optimal timing and duration for peak effectiveness are unclear.
- A study of 220 patients found that the peak improvement in the PaO2:FiO2 ratio during the first prone positioning episode occurred after about 9 hours.
- While subsequent prone episodes also improved oxygenation, their effectiveness was reduced, suggesting that guidelines for frequency and duration could be informed by these findings.
Background: The setting of tidal volume (V) during controlled mechanical ventilation (CMV) in critically ill patients without acute respiratory distress syndrome (ARDS) is likely important but currently unknown. We aimed to describe current CMV settings in intensive care units (ICUs) across Victoria.
Methods: We performed a multicentre, prospective, observational study.