Plasmonic Nanoparticles for Photothermal Therapy: Benchmarking of Photothermal Properties and Modeling of Heating at Depth in Human Tissues.

Many different types of nanoparticles have been developed for photothermal therapy (PTT), but directly comparing their efficacy as heaters and determining how they will perform when localized at depth in tissue remains complex. To choose the optimal nanoparticle for a desired hyperthermic therapy, it is vital to understand how efficiently different nanoparticles extinguish laser light and convert that energy to heat. In this paper, we apply photothermal mass conversion efficiency (η ) as a metric to compare nanoparticles of different shapes, sizes, and conversion efficiencies.

A systematic scoping review exploring variation in practice in specimen mammography for Intraoperative Margin Analysis in Breast Conserving Surgery and the role of artificial intelligence in optimising diagnostic accuracy.

Purpose: Specimen Mammography (SM) is commonly used in Breast Conserving Surgery (BCS) for intraoperative margin analysis. A systematic scoping review was conducted to identify sources of methodological variation in Specimen Mammography Interpretation (SMI) and assess the role of Artificial Intelligence (AI) techniques to optimise Diagnostic Accuracy (DA).

Methods: Embase, Pubmed, Cochrane and web of science databases were searched.

A step in the journey to food waste: How and why mealtime surpluses become unwanted.

This paper explores how and why Saudi householders designate mealtime leftovers as unwanted, thereby making them more likely to become waste. The paper argues that although over-provisioning is cited as one of the main antecedents for food waste, food becomes unwanted before it becomes waste and the designation of over-provisioned food as unwanted is an important but neglected driver of food waste. The study draws on in-depth interviews with 28 Saudi women to reveal four main reasons for the classification of leftovers as unwanted.

A triple-star system with a misaligned and warped circumstellar disk shaped by disk tearing.

Young stars are surrounded by a circumstellar disk of gas and dust, within which planet formation can occur. Gravitational forces in multiple star systems can disrupt the disk. Theoretical models predict that if the disk is misaligned with the orbital plane of the stars, the disk should warp and break into precessing rings, a phenomenon known as disk tearing.

Shedding new light on the (in)compatibility of chronic disease management with everyday life - social practice theory, mobile technologies and the interwoven time-spaces of teenage life.

This article uses a socio-material approach, social practice theory, to provide new insights into the self-management of chronic illness. It demonstrates how this theory can bridge arguments about the respective roles of social and individual influences, and how it can foreground an oft-overlooked aspect of the issue - the demands of self-care technologies and consequences for participation in social life. Drawing on interviews and focus groups with 25 young type-1 diabetes outpatients in London, UK, the study points to the conflicts that occur when disease management technologies compete for time and space with the social practices of everyday life, and when self-care tasks threaten to interrupt the flow of social life and make people feel 'left behind'.

Effectiveness of a smartphone app in increasing physical activity amongst male adults: a randomised controlled trial.

Background: Smartphones are ideal for promoting physical activity in those with little intrinsic motivation for exercise. This study tested three hypotheses: H1 - receipt of social feedback generates higher step-counts than receipt of no feedback; H2 - receipt of social feedback generates higher step-counts than only receiving feedback on one's own walking; H3 - receipt of feedback on one's own walking generates higher step-counts than no feedback (H3).

Methods: A parallel group randomised controlled trial measured the impact of feedback on steps-counts.

EXPLORING THE ORIGINS OF DEUTERIUM ENRICHMENTS IN SOLAR NEBULAR ORGANICS.

Deuterium-to-hydrogen (D/H) enrichments in molecular species provide clues about their original formation environment. The organic materials in primitive solar system bodies generally have higher D/H ratios and show greater D/H variation when compared to D/H in solar system water. We propose this difference arises at least in part due to (1) the availability of additional chemical fractionation pathways for organics beyond that for water, and (2) the higher volatility of key carbon reservoirs compared to oxygen.

Walking as a social practice: dispersed walking and the organisation of everyday practices.

This paper uses social practice theory to study the interweaving of walking into everyday practices and considers how greater awareness of everyday walking can influence its position within the organisation and scheduling of everyday life. Walking is of policy interest because of its perceived benefits for health. This paper asserts that increased awareness of everyday walking allows users to become more active without having to reschedule existing activities.

The ancient heritage of water ice in the solar system.

Identifying the source of Earth's water is central to understanding the origins of life-fostering environments and to assessing the prevalence of such environments in space. Water throughout the solar system exhibits deuterium-to-hydrogen enrichments, a fossil relic of low-temperature, ion-derived chemistry within either (i) the parent molecular cloud or (ii) the solar nebula protoplanetary disk. Using a comprehensive treatment of disk ionization, we find that ion-driven deuterium pathways are inefficient, which curtails the disk's deuterated water formation and its viability as the sole source for the solar system's water.