Publications by authors named "Tim Fitz"

Background/objectives: Advanced rectal cancer is one of the most common cancers worldwide and has a significant impact on public health. Because favorable and long-term survival has been achieved with multimodal therapy, patient quality of life is very important. The intention of this study was to assess patients' quality of life using various functioning and symptom scores from the years 2010 to 2022 and to examine changes over time.

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Objectives: This study evaluates the impact of a scanner-integrated, customized clinical decision support system (CDSS) on the acquisition technique, scan range, and reconstruction in thoracoabdominal CT.

Materials And Methods: We applied CDSS in contrast-enhanced examinations of the trunk with various clinical indications on a recent scanner with the capability of dual-energy CT (DECT), anatomic landmark detection (ALD), and iterative metal-artifact reduction (MAR). Simple and comprehensive questions about the patient's breath hold capability, the anatomical region of interest, and metal implants can be answered after the localizer.

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Colorectal cancer remains one of the most commonly diagnosed cancers. Advanced rectal cancer patients receive neoadjuvant radiochemotherapy as well as surgery and suffer from reduced health-related quality of life due to various side effects. We were interested in the role of the COVID-19 pandemic and how it affected those patients' quality of life.

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The aim of this study was to analyze the quality of life of patients with advanced rectal cancer before and during the COVID-19 pandemic and to determine whether the pandemic affected patients’ quality of life. The study included 389 patients and was performed from May 2010 to June 2021. The fifteen months from March 2020 to June 2021 were categorized as the COVID-19 period.

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Article Synopsis
  • Neoadjuvant radiochemotherapy and total mesorectal excision in advanced rectal cancer can significantly improve overall survival, with quality of life (QOL) being a key factor in prognosis.
  • A study involving 360 patients found that the "physical function" score from QOL questionnaires, along with symptoms like fatigue, nausea, pain, and appetite loss, strongly predicted overall survival outcomes.
  • Patients with a high baseline "physical function" score had an 8-year survival rate of 70.4%, while those with lower scores had a rate of 47.5%, suggesting that improving physical function post-diagnosis could potentially enhance survival rates.
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