Publications by authors named "Tim De Maayer"

Article Synopsis
  • Refeeding syndrome (RFS) is a serious and often overlooked complication in the treatment of severe acute malnutrition (SAM) in children, and this study focused on its occurrence and associated health issues in a South African hospital setting.
  • The study analyzed the medical records of 126 children diagnosed with SAM and found that 8.7% developed RFS during treatment, accompanied by significant clinical and biochemical abnormalities.
  • Children with RFS experienced longer hospital stays and higher rates of specific health issues like low potassium and sodium levels, dehydration, and urinary tract infections compared to those who did not develop RFS.
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Background: Pediatric acute liver failure (PALF) is an uncommon, devastating illness with significant mortality. Liver transplantation remains the mainstay of treatment for irreversible PALF. The purpose of this study was to determine the etiology and prognostic factors associated with outcome of PALF in South Africa and to evaluate prognostic scoring systems used.

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Coeliac disease (CD) is an autoimmune disorder and one of the few gastroenteropathies with accurate serological testing. CD serology has decreased accuracy for patients on a gluten-free diet and for monitoring mucosal healing. New ancillary tests would, therefore, be useful.

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Coeliac disease (CD) is an autoimmune gastroenteropathy triggered by gliadin and gliadin-tissue transglutaminase (tTG) complexes. CD is one of the few autoimmune diseases with an accurate, non-invasive serological test. Anti-endomysial, anti-tTG and anti-deaminated gliadin peptides (DGP) antibodies are currently used for serological tests with tTG ELISAs being the superior test.

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Background: The Health Professions Council of South Africa (HPCSA) issued early hearing detection and intervention guidelines, which has universal newborn hearing screening (UNHS) as one of the important goals. Despite established evidence of the importance of UNHS globally, there has been no mandated formalised and standardised implementation as yet in South Africa.

Objectives: The aim of this study was to describe the outcomes of newborn hearing screening (NHS) in an academic secondary level hospital in Johannesburg, South Africa.

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Although cryptococcal meningitis is uncommon in children and rare in neonates, it does occur. We highlight circumstances in which the diagnosis should be considered and methods required to confirm the diagnosis in young patients.

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Objective: Case death rates for severe childhood malnutrition remain stubbornly elevated in high HIV prevalence settings, despite the implementation of WHO guidelines. This study examined case death and other clinical outcomes in malnourished children with and without HIV infection.

Methods: A prospective, observational study was undertaken at three tertiary hospitals in Johannesburg, South Africa.

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Aim: To identify risk factors for severe childhood malnutrition in a rural South African district with a high HIV/AIDS prevalence.

Design: Case-control study.

Setting: Bushbuckridge District, Limpopo Province, South Africa.

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