Reliability of cortical lesion detection on double inversion recovery MRI applying the MAGNIMS-Criteria in multiple sclerosis patients within a 16-months period.

Purpose: In patients with multiple sclerosis (MS), Double Inversion Recovery (DIR) magnetic resonance imaging (MRI) can be used to identify cortical lesions (CL). We sought to evaluate the reliability of CL detection on DIR longitudinally at multiple subsequent time-points applying the MAGNIMs scoring criteria for CLs.

Methods: 26 MS patients received a 3T-MRI (Siemens, Skyra) with DIR at 12 time-points (TP) within a 16 months period.

Central versus thinnest pachymetry of the cornea and thinnest point vector length: impact of ocular side, refractive state, age, and sex.

Purpose: To quantify the difference in corneal thickness between the central and thinnest point (ΔCCT-TPCT) and the distance between the center of the cornea and its thinnest point (TPCT vector length) and to explore the impact of ocular side, refractive state, age, and sex.

Methods: Multicenter, retrospective, cross-sectional study. Medical records of 8054 eyes of 4027 refractive surgery candidates were reviewed.