Modeling Epistemic Uncertainty in Offshore Wind Farm Production Capacity to Reduce Risk.

Financial stakeholders in offshore wind farm projects require predictions of energy production capacity to better manage the risk associated with investment decisions prior to construction. Predictions for early operating life are particularly important due to the dual effects of cash flow discounting and the anticipated performance growth due to experiential learning. We develop a general marked point process model for the times to failure and restoration events of farm subassemblies to capture key uncertainties affecting performance.

Quantifying uncertainty about future antimicrobial resistance: Comparing structured expert judgment and statistical forecasting methods.

The increase of multidrug resistance and resistance to last-line antibiotics is a major global public health threat. Although surveillance programs provide useful current and historical information on the scale of the problem, the future emergence and spread of antibiotic resistance is uncertain, and quantifying this uncertainty is crucial for guiding decisions about investment in antibiotics and resistance control strategies. Mathematical and statistical models capable of projecting future rates are challenged by the paucity of data and the complexity of the emergence and spread of resistance, but experts have relevant knowledge.

Investing in antibiotics to alleviate future catastrophic outcomes: What is the value of having an effective antibiotic to mitigate pandemic influenza?

Over 95% of post-mortem samples from the 1918 pandemic, which caused 50 to 100 million deaths, showed bacterial infection complications. The introduction of antibiotics in the 1940s has since reduced the risk of bacterial infections, but growing resistance to antibiotics could increase the toll from future influenza pandemics if secondary bacterial infections are as serious as in 1918, or even if they are less severe. We develop a valuation model of the option to withhold wide use of an antibiotic until significant outbreaks such as pandemic influenza or foodborne diseases are identified.

Sequential Refined Partitioning for Probabilistic Dependence Assessment.

Modeling dependence probabilistically is crucial for many applications in risk assessment and decision making under uncertainty. Neglecting dependence between multivariate uncertainties can distort model output and prevent a proper understanding of the overall risk. Whenever relevant data for quantifying and modeling dependence between uncertain variables are lacking, expert judgment might be sought to assess a joint distribution.

Approximate Uncertainty Modeling in Risk Analysis with Vine Copulas.

Many applications of risk analysis require us to jointly model multiple uncertain quantities. Bayesian networks and copulas are two common approaches to modeling joint uncertainties with probability distributions. This article focuses on new methodologies for copulas by developing work of Cooke, Bedford, Kurowica, and others on vines as a way of constructing higher dimensional distributions that do not suffer from some of the restrictions of alternatives such as the multivariate Gaussian copula.

Decision making for group risk reduction: dealing with epistemic uncertainty.

Group risk is usually represented by FN curves showing the frequency of different accident sizes for a given activity. Many governments regulate group risk through FN criterion lines, which define the tolerable location of an FN curve. However, to compare different risk reduction alternatives, one must be able to rank FN curves.

A Bayes linear Bayes method for estimation of correlated event rates.

Typically, full Bayesian estimation of correlated event rates can be computationally challenging since estimators are intractable. When estimation of event rates represents one activity within a larger modeling process, there is an incentive to develop more efficient inference than provided by a full Bayesian model. We develop a new subjective inference method for correlated event rates based on a Bayes linear Bayes model under the assumption that events are generated from a homogeneous Poisson process.

A role for human reliability analysis (HRA) in preventing drinking water incidents and securing safe drinking water.

The prevalence of water quality incidents and disease outbreaks suggests an imperative to analyse and understand the roles of operators and organisations in the water supply system. One means considered in this paper is through human reliability analysis (HRA). We classify the human errors contributing to 62 drinking water accidents occurring in affluent countries from 1974 to 2001; define the lifecycle of these incidents; and adapt Reason's 'Swiss cheese' model for drinking water safety.