Markers of consciousness in infants: Towards a 'cluster-based' approach.

As recently as the 1980s, it was not uncommon for paediatric surgeons to operate on infants without anaesthesia. Today, the same omission would be considered criminal malpractice, and there is an increased concern with the possibility of consciousness in the earliest stage of human infancy. This concern reflects a more general trend that has characterised science since the early 1990s of taking consciousness seriously.

Tests for consciousness in humans and beyond.

Which systems/organisms are conscious? New tests for consciousness ('C-tests') are urgently needed. There is persisting uncertainty about when consciousness arises in human development, when it is lost due to neurological disorders and brain injury, and how it is distributed in nonhuman species. This need is amplified by recent and rapid developments in artificial intelligence (AI), neural organoids, and xenobot technology.

Consciousness in the cradle: on the emergence of infant experience.

Although each of us was once a baby, infant consciousness remains mysterious and there is no received view about when, and in what form, consciousness first emerges. Some theorists defend a 'late-onset' view, suggesting that consciousness requires cognitive capacities which are unlikely to be in place before the child's first birthday at the very earliest. Other theorists defend an 'early-onset' account, suggesting that consciousness is likely to be in place at birth (or shortly after) and may even arise during the third trimester.

Not with a "zap" but with a "beep": Measuring the origins of perinatal experience.

When does the mind begin? Infant psychology is mysterious in part because we cannot remember our first months of life, nor can we directly communicate with infants. Even more speculative is the possibility of mental life prior to birth. The question of when consciousness, or subjective experience, begins in human development thus remains incompletely answered, though boundaries can be set using current knowledge from developmental neurobiology and recent investigations of the perinatal brain.

Theories of consciousness.

Recent years have seen a blossoming of theories about the biological and physical basis of consciousness. Good theories guide empirical research, allowing us to interpret data, develop new experimental techniques and expand our capacity to manipulate the phenomenon of interest. Indeed, it is only when couched in terms of a theory that empirical discoveries can ultimately deliver a satisfying understanding of a phenomenon.

Consciousness after split-brain surgery: The recent challenge to the classical picture.

In a recent series of experiments, Pinto and colleagues found that the split-brain patient D.D.C.

Split-Brain: What We Know Now and Why This is Important for Understanding Consciousness.

Recently, the discussion regarding the consequences of cutting the corpus callosum ("split-brain") has regained momentum (Corballis, Corballis, Berlucchi, & Marzi, Brain, 141(6), e46, 2018; Pinto et al., Brain, 140(5), 1231-1237, 2017a; Pinto, Lamme, & de Haan, Brain, 140(11), e68, 2017; Volz & Gazzaniga, Brain, 140(7), 2051-2060, 2017; Volz, Hillyard, Miller, & Gazzaniga, Brain, 141(3), e15, 2018). This collective review paper aims to summarize the empirical common ground, to delineate the different interpretations, and to identify the remaining questions.

Are There Islands of Awareness?

Ordinary human experience is embedded in a web of causal relations that link the brain to the body and the wider environment. However, there might be conditions in which brain activity supports consciousness even when that activity is fully causally isolated from the body and its environment. Such cases would involve what we call islands of awareness: conscious states that are neither shaped by sensory input nor able to be expressed by motor output.

What is cognition?

Eleven authors with disparate relevant backgrounds give their view on what is meant by the word "cognition".

Dimensions of consciousness and the psychedelic state.

It has often been suggested in the popular and academic literature that the psychedelic state qualifies as a higher state of consciousness relative to the state of normal waking awareness. This article subjects this proposal to critical scrutiny, focusing on the question of what it would mean for a state of consciousness to be 'higher'. We begin by considering the contrast between conscious contents and conscious global states.

On the axiomatic foundations of the integrated information theory of consciousness.

The integrated information theory (IIT) is one of the most influential scientific theories of consciousness. It functions as a guiding framework for a great deal of research into the neural basis of consciousness and for attempts to develop a consciousness meter. In light of these developments, it is important to examine whether its foundations are secure.

Reforming the taxonomy in disorders of consciousness.

This article examines the serious shortcomings that characterize the current taxonomy of postcomatose disorders of consciousness (DoC), and it provides guidelines for how an improved DoC taxonomy might be developed. In particular, it is argued that behavioral criteria for the application of DoC categories should be supplemented with brain-based criteria (eg, information derived from electroencephalography and functional magnetic resonance imaging), and that the categorical framework that currently characterizes DoC should be replaced by a multidimensional framework that better captures the performance of patients across a range of cognitive and behavioural tasks. Ann Neurol 2017;82:866-872.

Are There Levels of Consciousness?

The notion of a level of consciousness is a key construct in the science of consciousness. Not only is the term employed to describe the global states of consciousness that are associated with post-comatose disorders, epileptic absence seizures, anaesthesia, and sleep, it plays an increasingly influential role in theoretical and methodological contexts. However, it is far from clear what precisely a level of consciousness is supposed to be.

Concepts, contents, and consciousness.

In his paper 'Are we ever aware of concepts? A critical question for the Global Neuronal Workspace, Integrated Information, and Attended Intermediate-Level Representation theories of consciousness' (2015, this journal), Kemmerer defends a conservative account of consciousness, according to which concepts and thoughts do not characterize the contents of consciousness, and then uses that account to argue against both the Global Neuronal Workspace theory of consciousness and Integrated Information Theory of Consciousness, and as a point in favour of Prinz's Attended Intermediate-level Representations theory. We argue that there are a number of respects in which the contrast between conservative and liberal conceptions of the admissible contents of consciousness is more complex than Kemmerer's discussion suggests. We then consider Kemmerer's case for conservatism, arguing that it lumbers liberals with commitments that they need not - and in our view should not - endorse.

Global disorders of consciousness.

In recent decades there has been a great deal of interest in global disorders of consciousness, such as the vegetative state, the minimally conscious state, and epileptic absence seizures. Global disorders of consciousness pose significant challenges to consciousness science in that the ordinary pretheoretical criteria for the ascription of consciousness are not easily applied in such contexts, and it is often unclear what kinds of conscious states-if any-patients are in. At the same time, global disorders of consciousness also promise to reveal a great deal about the nature of consciousness and the relationship between consciousness and cognitive and behavioral control.

The presence of consciousness in absence seizures.

This paper examines three respects in which the study of epileptic absence seizures promises to inform our understanding of consciousness. Firstly, it has the potential to bear on debates concerning the behavioural and cognitive functions associated with consciousness. Secondly, it has the potential to illuminate the relationship between background states (or 'levels') of consciousness and the contents of consciousness.

The Vegetative State and the Science of Consciousness.

Consciousness in experimental subjects is typically inferred from reports and other forms of voluntary behaviour. A wealth of everyday experience confirms that healthy subjects do not ordinarily behave in these ways unless they are conscious. Investigation of consciousness in vegetative state patients has been based on the search for neural evidence that such broad functional capacities are preserved in some vegetative state patients.

Delusion and confabulation: mistakes of perceiving, remembering and believing.

This paper adopts an inclusive approach to the relationship between delusion and confabulation, according to which some symptoms might qualify as both delusional and confabulatory. Our initial focus is on the cardinal signs of delusions: incomprehensibility, incorrigibility, and subjective conviction. Setting aside post hoc (or secondary) confabulations-plausible rationalisations that might be generated by nonpathological belief formation processes-we focus on spontaneous memory-based confabulations which, we suggest, conform to the characterisation of delusions.