Constant Desbordes Painting of Jean-Louis Alibert Administering the Smallpox Vaccine ("La Vaccine"): An Historic Vaccination or Artistic Imagination?

In 1822, France's Ministry of the Interior, concerned about dropping vaccination rates among the population, commissioned the French artist Constant Joseph Desbordes (1761-1828) to create an artwork that would educate the public about the benefits of the smallpox vaccine. The Painting that resulted is entitled: "La Vaccine" ("The Cowpox Inoculation") and a copy of it is entitled "La Vaccine au Chateau de Liancourt" ("Performing the Vaccination against Smallpox in the Chateau of Liancourt"). The highlight of the painting is its central figure, one of France's most distinguished physicians, Jean-Louis Alibert (1768-1837) performing, in dramatic fashion, the arm to arm method of smallpox vaccination that was common at that time.

[The Museum of the Hôpital Saint-Louis].

In 1866, Alphonse Devergie, physician supported by Armand Husson, manager of the Assistance publique created a permanent exhibition of teaching images of skin diseases at the Hôpital Saint-Louis (Paris). Twenty-five years later the initiative was made concrete by the inauguration of a building housing a museum, a medical library and rooms for outpatients. Enriched by the works of dermatologists, moulageurs - mainly Jules Baretta -, painters and photographs the museum became worldwide renown exhibiting the largest wax moulages collection of the world.

Acne pathogenesis: history of concepts.

From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process.

[History of the Journées Dermatologiques de Paris].

Founded in 1801 at the Hôpital Saint-Louis, Paris, under Jean-Louis Alibert, the French School of Dermatology was initially structured around the French Society of Dermatology (1889) and the organization of two world congresses (Paris 1889, 1900). After World War I, the creation of dermatological societies in the provinces infused French dermatology with new energy. In 1922, the first congress of the French-speaking dermatologists further contributed to the public profile of dermatologists in France.

The historical basis of a misconception leading to undertreating atopic dermatitis (eczema): facts and controversies.

The quest for clarifying the pathophysiology of atopic dermatitis (eczema) has lasted for 25 centuries. Yearning to discern the primum movens of atopic dermatitis, physicians aimed to identify the curative therapy. Recent scientific efforts has brought to the light an ever-growing amount of interplaying pathophysiologic factors, including the epidermal barrier, the digestive flora, food, early infections and antigenic stimulations, and innate and adaptive immune response; however, overfocusing on some of these factors, along with misconceptions about the benefit/risk balance of topical therapies, has sometimes led topical therapies being disregarded.

Topical therapy of atopic dermatitis: controversies from Hippocrates to topical immunomodulators.

Although atopic dermatitis can be treated efficiently, there is still much controversy about the risk/benefit ratio of both topical corticosteroids and topical immunomodulators. Conflicting data may be found about the usefulness of bathing, diet regulation, and other therapeutic interventions. These controversies result in part from the persistence of Hippocratic doctrines in modern medical thinking.

The first images of atopic dermatitis: an attempt at retrospective diagnosis in dermatology.

Background: Atopic dermatitis was defined in 1933. Earlier descriptions have yet not been thoroughly studied.

Objective: Our purpose was to identify the first images of atopic dermatitis among historical illustrations of skin diseases.

[1801-2001: two centuries of dermatology and venereology in the Assistance Publique-Hôpitaux de Paris].

The specialization "Dermatology" was born at the Saint-Louis hospital in France in 1801, in the light of the revolutionary reforms that led to fundamental changes in the functioning of the hospitals in Paris. Hence, the Saint-Louis hospital occupies an eminent position in the history of dermatology in France, reinforced by the role of Jean-Louis Alibert, who founded the French school of Dermatology. Despite the place occupied by the physicians of the Saint-Louis Hospital in the creation and development of the French school of dermatology, other physicians in other hospitals contributed to the expansion of the dermatology school.