Whole-genome sequencing of a CTX-M-11-encoding and quinolone-non-susceptible Klebsiella pneumoniae ST194 isolate from a hospitalised dog in Greece.

Objectives: The emergence and spread of transferable β-lactamases among Enterobacteriaceae is a major problem both to human and veterinary medicine and is an important contributing factor to the development of multidrug-resistant bacterial isolates. In the present study, whole-genome sequencing of a Klebsiella pneumoniae isolate (LKP817909) resistant to first- and second-generation cephalosporins and non-susceptible to fluoroquinolones, isolated from a urine sample of a hospitalised dog, was performed.

Methods: Genome sequencing was performed on an Illumina MiniSeq Sequencing System.

Effect of intrafragmentary bupivacaine (haematoma block) on analgesic requirements in dogs undergoing fracture repair.

Objective: To test the efficacy of intraoperative intrafragmentary administration of bupivacaine (haematoma block) in controlling postoperative pain in dogs undergoing osteosynthesis of long-bone isolated diaphyseal fractures.

Study Design: Randomized, 'blinded', placebo-controlled, prospective study.

Animals: A total of 23 client-owned dogs with isolated long-bone fractures.

Gastro-oesophageal reflux in large-sized, deep-chested versus small-sized, barrel-chested dogs undergoing spinal surgery in sternal recumbency.

Objective: The aim of this study was to investigate whether an increased frequency of gastro-oesophageal reflux (GOR) is more common in large-sized, deep-chested dogs undergoing spinal surgery in sternal recumbency than in small-sized, barrelchested dogs.

Study Design: Prospective, cohort study.

Animals: Nineteen small-sized, barrel-chested dogs (group B) and 26 large-sized, deep-chested dogs (group D).

Urothorax Associated with Uroperitoneum in a Dog Without Diaphragmatic Disruption.

Accumulation of urine in the pleural space secondary to uroperitoneum with no disruption of the diaphragm appears to be a rare pathological condition. A 2 yr old male mixed-breed dog was referred with dyspnea and abdominal pain after a road traffic accident. Plain radiographs demonstrated pleural effusion and reduced serosal detail in the abdominal cavity that was compatible with fluid accumulation.

The effect of the stage of the ovarian cycle (anoestrus or dioestrus) and of pregnancy on the incidence of gastro-oesophageal reflux in dogs undergoing ovariohysterectomy.

Objective: To investigate the potential association of increased blood progesterone (P4 ) concentrations and/or late pregnancy with the incidence of gastro-oesophageal reflux (GOR), in healthy bitches undergoing ovariohysterectomy under general anaesthesia during anoestrus or dioestrus or during the second half of pregnancy.

Study Design: Prospective observational study.

Animals: Ninety-four healthy, female, dogs, aged 1-8 years presented for elective ovariohysterectomy.

Anesthesia and perioperative management of a pneumonectomized dog.

Although left- or right-sided pneumonectomy is tolerated by normal dogs, complications impacting the respiratory, cardiovascular, and gastrointestinal systems are not uncommon. Pneumonectomy in dogs results in secondary changes in the remaining lung, which include: decreased compliance and vital capacity; and increased pulmonary vascular resistance potentially leading to right ventricular hypertrophy. Such alterations make the anesthetic management of an animal with one lung particularly challenging.

Remifentanil/isoflurane anesthesia in five dogs with liver disease undergoing liver biopsy.

Remifentanil is a synthetic opioid with direct action on μ opioid receptors. It has an ultrashort duration of action, and its elimination is independent of hepatic or renal function. The anesthetic management of five dogs with nonuniform liver disease and requiring liver biopsy via celiotomy is described.

Evaluation of the effectiveness of an ointment based on Alkannins/Shikonins on second intention wound healing in the dog.

The enantiomeric naphthoquinones alkannins and shikonins (A/S) have been established as potent wound healing agents. The purpose of this study was to evaluate the effectiveness of an A/S based ointment for humans on second intention wound healing in the dog, as compared to wound flushing with Lactated Ringer's solution (LRS). Ten mixed breed dogs, aged 2 to 5 y, were used.

Naturally occurring isohexenylnaphthazarins and wound healing: experimental study in dogs.

Background: The healing efficacy of isohexenylnaphthazarins (IHN) has been well proved on chronic or contaminated wounds.

Objective: To evaluate the wound healing activity of an experimental ointment containing IHN on acute and noncontaminated wounds in dogs.

Methods: In each of six beagle dogs, four full-thickness skin defects were created bilaterally: one 2 x 2 cm defect on the lateral aspect of each arm for subjective evaluation, laser Doppler flowmetry (LDF), and planimetry and three 1.

Effect of endogenous progesterone and oestradiol-17beta on the incidence of gastro-oesophageal reflux and on the barrier pressure during general anaesthesia in the female dog.

Objective: To investigate the potential effect of increased blood progesterone (P(4)) and oestradiol-17beta (E(2)) concentrations on the barrier pressure (BrP) and the incidence of gastro-oesophageal reflux (GOR) in female dogs under general anaesthesia.

Study Design: Prospective, blinded experimental trial.

Animals: Seven female, adult, healthy dogs weighing 14-21 kg and aged 1-7 years.

Thiopental and halothane dose-sparing effects of magnesium sulphate in dogs.

Objective: To evaluate the effect of pre- and intraoperatively administered magnesium sulphate (MgSO(4)) on the induction dose of thiopental and of halothane for maintenance of anaesthesia in dogs undergoing ovariohysterectomy (OHE).

Study Design: Prospective, double-blind, randomized, placebo-controlled study.

Animals: Forty-six healthy, ASA physical status 1 dogs, scheduled for elective OHE.