Publications by authors named "Tilemachos Karalis"

Purpose: When oncological waiting lists are prolonged, gynecological oncology units are forced to delay operations, especially for endometrial cancer (EC) due to its good prognosis among gynecological cancers. The aim of this study is to evaluate the impact of delay in the oncological outcomes of these patients.

Methods: This is a retrospective analysis of all women with EC treated in our clinic, 2012-2019.

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Introduction And Hypothesis: Various instruments are used to evaluate the severity of stress urinary incontinence (SUI) in clinical trials for SUI surgery. We conducted a scoping review with the primary aim of investigating the use of such instruments.

Methods: A comprehensive search in PubMed/MEDLINE, Cochrane Library, ClinicalTrials.

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Introduction And Hypothesis: The objective was to present endoscopic images of a meshoma and describe the complete excision of a complicated mesh after sacrocolpopexy (SCP) using a combined vaginal-endoscopic technique.

Methods: We present a video documentation of an innovative technique. A 58-year-old woman was referred with painless, foul-smelling vaginal discharge and recurrent vaginal mesh erosions.

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Introduction During menopause, healthy women experience a diverse aggregate of clinical manifestations and symptoms that relate to hormonal and aging changes. These alterations are strictly associated with psychological disorders, mainly depression. Estrogen treatment may be effective for these mood variations caused by menopause.

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Article Synopsis
  • This study evaluated the effectiveness and outcomes of using polyvinylidene difluoride (PVDF) compared to polypropylene (PP) in surgeries for stress urinary incontinence (SUI) and pelvic organ prolapse (POP) over the last 25 years.
  • A systematic review and meta-analysis were conducted, analyzing various studies that provided numeric data on the post-operative results, while excluding certain patient populations to ensure quality and accuracy in findings.
  • Primary outcomes focused on rates of post-operative recurrence, mesh erosion, and pain, while secondary outcomes included sexual dissatisfaction and other post-operative complications.
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Introduction Peripheral neuropathy is one of the possible complications of diabetes. Alpha-lipoic acid (a-lipoic acid or ALA) is a powerful antioxidant cofactor synthesized in mitochondria that could help stimulate nerves and regenerate nerve fibers, thus preventing disease progression. Moreover, the possible feeling of oppression from the lifestyle changes needed to avoid the complications of diabetes may contribute to the development of depressive symptoms.

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Introduction: L-Carnitine is a very important component of the human body which is involved in cardiac function and generally in the proper functioning of the muscular system. Also, it contributes to the proper use of glucose by the cell, thereby improving the regulation of glucose metabolism of the diabetic patient and preventing complications such as fatigue, insomnia, and mental activity. In this paper we would like to show the therapeutic effect of L-carnitine on type II diabetic patients after 2 g/day oral administration of L-carnitine.

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It is a common ground that humans have always modified the genome of both plants and animals. This intrusive process that has existed for thousands of years, many times through mistakes and failures, was initially carried out through the crossing of organisms with desirable features. This was done with the aim of creating and producing new plants and animals that would benefit humans, that is , they would offer better quality food, more opportunities for people to move and transport products, greater returns to work, resistance to diseases, etc.

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