[Morphological changes of rat ovaries after their monopolar coagulation and ascovertin correction].

Using the methods of light and electron microscopy, morpho-functional changes of the ovaries of albino rats after their monopolar coagulation were studied. Electrocoagulation was shown to cause hemodynamic changes in a perifocal area and short-term stimulation of follicular growth, but starting already at postoperational day 3, their atresia was increased, while by day 30 a significant reduction in number of both primordial and growing follicles, as well as of corpora lutea, was found. Ultrastructural changes of oocytes in primary and secondary follicles outside the coagulation zone were demonstrated at early stages and included the reduction of porous plate, cortical and yolk granule numbers, and the increase in numbers of lysosomes and multivesicular bodies.

[Electrophoresis of sulphide mud extract in combined therapy of chronic inflammatory diseases of uterine appendages (an experimental and clinical study)].

On the original experimental model of chronic inflammation of the ovaries and oviducts in white rats it was established that electrophoresis of 1% esobel solution prevents an increase in the specific volume of interstitial connective tissue, development of fibrosclerotic alterations and adhesive process. Peloidophysiotherapy normalizes growth and atresia of the ovarian follicular system. Thus, electrophoresis of 1% esobel solution is highly effective in combined treatment of chronic inflammatory diseases of the uterine appendages.

[Effect of peloid therapy on morphofunctional changes of ovaries and oviducts caused by suturing (experimental study)].

A course of ultraphonophoresis of the extract of high-polar lipids of sulfide mud attenuated inflammation of uterine appendages in rats caused by catgut suturing of the ovaries and oviducts. On postoperative day 75-120 peloid therapy resulted in degradation of the suture material and its replacement with connective tissue. The peloid limited postoperative intensification of follicular atresia, raised content of growing follicles and yellow bodies in the ovaries.

[Method for treating inflammatory diseases of the uterine appendages using the eplir mud preparation].

Ultraphonophoresis of 1% oil solution of eplir in patients with acute inflammation of the uterine appendages as an adjuvant to drug therapy enhances the latter by immediate (anesthetic, antiexudative action), short-term (immunocorrection) and long-term (preservation and restoration of reproductive function, prevention of chronicity) treatment results.

[An experimental and clinical validation of a method for treating acute inflammatory diseases of the adnexa uteri by using the electrophoresis of a therapeutic mud preparation].

Experimental and clinical investigations have demonstrated that the addition of abdominal-sacral electrophoresis of esobel 1% solution to combined therapy of acute inflammation of the uterine appendages improves treatment results. Bioantioxidants bring about the antiinflammatory action of the mud preparation esobel while its high-polar lipids prevent structural-metabolic impairment of the appendages' tissue elements as shown by a pronounced antiexudative effects and weak secondary alteration.

[The ultrastructural changes to the ovaries and oviducts in experimental inflammation under the influence of eplir phonophoresis].

Ultrastructural changes of blood vessels of ovaries and oviducts, destruction of the part of follicular epitheliocytes and disruption of other structures of blood-follicular barrier occur at the early period of experimental inflammations of appendage uterus on the background of traditional antibiotic therapy. All changes lead to atresia of growing follicules. Fibrotic-sclerotic changes develop on the 30th day and during later period.

[An experimental validation of the use of the ultraphonophoresis of the mud preparation Eplir in inflammation of the uterine adnexa].

Eplir ultraphonophoresis started on day 5 of experimental inflammation of the uterine appendages in the presence of antibacterial therapy reduces the severity of exudative processes, hemodynamic disorders, leukocytic infiltration, follicular atresia, prevents growth of connective tissue stroma.

[The effect of the brine and mud extract from Lake Karachi on the morphofunctional status of the adnexa uteri in experimental inflammation].

Two-stage electrophoresis of preparations made of natural brine and extract of mud taken from the Lake Karachi tried in combined treatment of experimental inflammation of the uterine appendages prevents proliferative and sclerotic alterations in ovarian stroma, stimulates repair of the intramural nerves, corrects follicular atresia.