Use of the levonorgestrel-releasing intrauterine system and breast cancer.

Objective: The effect of exogenous hormones on the incidence of breast cancer has been extensively studied. Most studies regarding hormonal contraception have focused on combined oral contraceptives, and there is paucity of literature regarding nonoral and progestin-only contraceptives. The present study analyzed the relationship between breast cancer and use of the levonorgestrel-releasing intrauterine system.

Benefit-risk assessment of the levonorgestrel intrauterine system in contraception.

The levonorgestrel-releasing intrauterine system (IUS) is a long-acting, fully reversible method of contraception. It is one of the most effective forms of contraception available, and combines the advantages of both hormonal and intrauterine contraception. The levonorgestrel-releasing IUS also gives the users many non-contraceptive benefits: the amount of menstrual bleeding and the number of days of menstrual bleeding are reduced, which makes it suitable for the treatment of menorrhagia (heavy menstrual blood loss).

Concomitant vaginal surgery did not affect outcome of the tension-free vaginal tape operation during a prospective 3-year followup study.

Purpose: We compare outcomes when vaginal surgery and a tension-free vaginal tape (TVT) operation were done concomitantly and when only a TVT operation was done in patients with stress or mixed urinary incontinence.

Materials And Methods: Outcomes in 75 consecutive patients who underwent a TVT operation concomitantly with vaginal surgery (group 1) were compared with outcomes in 75 who underwent only a TVT operation (group 2) between August 1998 and June 2000. Group 2 patients were matched for age and incontinence type with group 1 patients.

Pregnancy during the use of levonorgestrel intrauterine system.

Objectives: This study was undertaken to evaluate the pregnancy rate with the levonorgestrel intrauterine system (LNG IUS) and to analyze the outcome of pregnancies with the LNG IUS in situ in regular use.

Study Design: Questionnaires from 17,360 users of the LNG IUS were analyzed. With the consent of women reporting pregnancy during the use of the LNG IUS, related hospital records were reviewed concerning the pregnancies.

Advance information improves user satisfaction with the levonorgestrel intrauterine system.

Objective: To evaluate parameters associated with and the impact of advance information given in a regular outpatient setting on user satisfaction with the levonorgestrel-releasing intrauterine system.

Methods: A questionnaire was sent to 23,885 women in Finland who had had a levonorgestrel intrauterine system inserted between 1990 and 1993. The number of returned questionnaires was 17,914 (response rate 75%).