Successful management of idiopathic early-onset scoliosis: effect of curve correction and bracing after Mehta casting.

Study Design: Patients with idiopathic EOS treated by Mehta casting followed by bracing or observation from a single institution.

Objectives: To determine casting protocol parameters leading to successful management; to determine efficacy of bracing vs. observation after cast discontinuance.

Understanding resistant hypertension.

Resistant hypertension affects about 17% of the US population. However, it is difficult to diagnose because of multiple factors that influence adequate treatment of BP, including patient lifestyle and comorbidities, improper therapeutic regimens, and secondary mechanisms. Possible causes of resistant hypertension include nonmodulator hypertension, which affects patients who have an inappropriate response to elevated sodium through the renin-angiotensin-aldosterone system.

Effect of Copolymer Structure on Rare-Earth-Element Chelation Thermodynamics.

Rare-earth elements (REEs) are crucial to modern technology, leading to a high demand for materials capable of REE extraction and purification. Metal-chelating polymers (e.g.

Teen Driving Education in a Pediatric Emergency Department: Effectiveness of a Toolkit.

Objectives: In the United States, the leading cause of death for adolescents aged 16 to 24 years is motor vehicle crashes, with Alabama ranked as the second-worst state in the nation for teen driving deaths. We sought to determine the efficacy of teenage driving education within the setting of the pediatric emergency department and to assess the driving habits of teenagers and their parents and their understanding of the Alabama Graduated Driver's License (GDL) law.

Methods: Surveys were administered to noncritically ill teenagers aged 13 to 19 years and their parents who presented to the children's emergency department.

The RAB39B p.G192R mutation causes X-linked dominant Parkinson's disease.

Objective: To identify the causal gene in a multi-incident U.S. kindred with Parkinson's disease (PD).

The effect of anxiety and depression on symptoms attributed to atrial fibrillation.

Background: Symptoms attributed to atrial fibrillation (AF) are nonspecific, and it remains unclear what influences perception of symptoms. Anxiety or depression may be important in modulating perception of AF symptoms. However, few longitudinal studies have addressed this effect.

Educational attainment is associated with atrial fibrillation symptom severity.

Background: Atrial fibrillation (AF), the most common arrhythmia encountered in clinical practice, is often managed with a rhythm control strategy. Despite the emphasis on symptom relief as the motivation for a rhythm controlling strategy in AF, it remains unclear what factors affect the patient's experienced severity of AF symptoms. We hypothesize that demographic variables may affect AF symptom severity as many AF symptoms (palpitations, dyspnea, fatigue) are nonspecific and may require particular patient insight.