Publications by authors named "Tiffany Ming"

Background: This study aims to understand the demographic representation of patients in Traumatic Brain Injury (TBI) clinical trials by evaluating the proportions of patients from various demographic categories amongst completed TBI clinical trials in the United States.

Methods: ClinicalTrials.gov was queried for active TBI clinical trials.

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Background: Disparities in neurosurgical care have emerged as an area of interest when considering the impact of social determinants on access to health care. Decompression via anterior cervical discectomy and fusion (ACDF) for cervical stenosis (CS) may prevent progression towards debilitating complications that may severely compromise one's quality of life. This retrospective database analysis aims to elucidate demographic and socioeconomic trends in ACDF provision and outcomes of CS-related pathologies.

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Article Synopsis
  • Spinal meningiomas are benign tumors that can cause neurological problems, and their treatment varies based on patient characteristics, but there's a lack of clear guidelines for selecting patients for surgery.
  • In a study analyzing data from 6395 patients, it was found that 91.4% underwent surgery, with certain factors like elective admission status being positive predictors for surgery, while factors such as low income and obesity were negative predictors.
  • The surgical patients had fewer complications and comorbidities compared to the nonsurgical group, indicating that some patients may be underserved in accessing surgical treatment for spinal meningiomas.
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Background: Traumatic spinal injury (TSI) can lead to severe morbidity and significant health care resource utilization. Intraoperative navigation (ION) systems have been shown to improve outcomes in some populations. However, controversy about the benefit of ION remains.

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Synaptic connectivity within adult circuits exhibits a remarkable degree of cellular and subcellular specificity. We report that the axon guidance receptor Robo2 plays a role in establishing synaptic specificity in hippocampal CA1. In vivo, Robo2 is present and required postsynaptically in CA1 pyramidal neurons (PNs) for the formation of excitatory (E) but not inhibitory (I) synapses, specifically in proximal but not distal dendritic compartments.

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