Publications by authors named "Tiffany McAllister"
Previous preclinical and translational studies suggest that tissue trauma related to bony fracture and intervertebral disk disruption initiates the formation of pronociceptive antibodies that support chronic musculoskeletal pain conditions. This study tested this hypothesis in the monosodium iodoacetate (MIA) mouse model of osteoarthritis (OA) and extended the findings using OA patient samples. Monosodium iodoacetate was injected unilaterally into the knees of male and female wild-type (WT) and muMT mice (lacking B cells) to induce articular cartilage damage.
View Article and Find Full Text PDFArticle Synopsis
- - The study aimed to find out if analyzing the immune response through single-cell and plasma proteomic data could predict surgical site complications (SSCs) after major abdominal surgery.
- - Researchers collected and analyzed blood samples from 41 patients before surgery and on the first postoperative day, discovering that a model based on this data could effectively differentiate patients who would develop SSCs.
- - The findings indicated that certain immune responses, both before and after surgery, could serve as reliable indicators for predicting SSCs, suggesting a potential for improved risk assessment in surgical patients.
Approximately 8.3% of the U.S.
View Article and Find Full Text PDF