Thermal sensitisation by lonidamine of human melanoma cells grown at low extracellular pH.

Purpose: This study tested the ability of lonidamine (LND), a clinically applicable inhibitor of monocarboxylate transporters (MCT), to thermally sensitise human melanoma cells cultured at a tumour-like extracellular pH (pHe) 6.7.

Materials And Methods: Human melanoma DB-1 cells cultured at pHe 6.