Publications by authors named "Tieying Yu"
Article Synopsis
- The epidermal growth factor receptor (EGFR) is a crucial protein involved in cell growth and development, particularly in scallops.
- Hybrid scallops from hermaphroditic bay and Peruvian scallops are mostly infertile, and this study explores the role of EGFR in this sterility via single-cell RNA sequencing.
- Findings show that lower levels of EGFR in infertile hybrids correspond to slower oocyte development and higher production of reactive oxygen species (ROS), which may lead to energy deficiencies and higher rates of cell death.
Article Synopsis
- Inter-specific hybrid scallops, created from bay and Peruvian scallops, show significant growth advantages but are sterile, limiting their use in breeding.
- This study utilized genome re-sequencing and transcriptomic analysis to identify genetic variations and differentially expressed genes linked to the sterility of these hybrids.
- A total of 24 genes related to fertility processes were identified, suggesting that factors like cell division and gamete development are disrupted in sterile hybrids, which impacts their potential in scallop breeding initiatives.
DNA methylation is an important epigenetic modification factor in regulating fertility. Corresponding process remains poorly investigated in hermaphroditic scallops. The interspecific F hybrids between the hermaphroditic bay scallops (Argopecten irradians) and Peruvian scallops (Argopecten purpuratus) exhibited significant heterosis in yield, but sterility in hybrids obstructs the utilization of the genetic resources.
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