A Study on Relationship of Hounsfield Units Value on Non-contrast Computer Tomography and Recanalization of Intravenous Thrombolysis.

Objective: The objective of this study is to determine whether the administration of intravenous alteplase would be beneficial or futile to patients with acute ischemic stroke caused by large vessel occlusion (LVO) before endovascular treatment (EVT) and determine the relationship between Hounsfield units (HU) in non-contrast computed tomography (NCCT) and recanalization by alteplase.

Methods: We performed a retrospective analysis of patients with acute ischemic stroke caused by LVO who received intravenous thrombolysis (IVT) or followed by EVT at our center during November 2016 and October 2020. The clinical characteristics and imaging features of patients who achieved recanalization after IVT, and those who did not, were compared.