Publications by authors named "Tielin Ning"
Background: Social app recruiting-based and peer-led testing strategies have been proven effective in increasing human immunodeficiency virus (HIV) testing among men who have sex with men (MSM), though their combination remains underevaluated. We aimed to assess the efficiency of a combined strategy named "standardly trained peer volunteer-led, social app recruiting-based HIV testing strategy using rapid testing kits" (SPARK).
Methods: Between March 2020 and December 2021, 177 trained peer volunteers tested 7256 eligible MSM testers.
Background: Men who have sex with men (MSM) are vulnerable to HPV infection. This study aims to explore the HPV infection status at different sites among HIV-positive MSM, HIV-negative MSM, and men who have sex with women (MSW), and to investigate their willingness to receive HPV vaccination.
Methods: From September 2023 to April 2024, three groups were recruited in Tianjin, China.
Article Synopsis
- The study examined drug resistance in HIV among newly diagnosed individuals in China from 2018 to 2023 to adapt treatment guidelines.
- Out of over 22,000 individuals, 4.36% had at least one transmitted drug resistance (TDR) mutation, with the most common being linked to nonnucleoside reverse transcriptase inhibitors.
- The prevalence of TDR mutations notably increased from 4.05% to 5.39% over the study years, supporting the ongoing use of NNRTI-based treatment regimens for HIV.
Article Synopsis
- China adopted the WHO's "treat all" policy in 2016, aiming to improve HIV care through the 95-95-95 targets, which include diagnosing 95% of HIV positive individuals, getting 95% of those diagnosed on treatment, and achieving viral suppression in 95% of treated individuals.
- Data from 2004 to 2023 showed significant advancements in these targets, correlating with a drop in new HIV infections, as evidenced by a dip in clustering frequency and a peak in cases documented in 2014.
- The study concludes that while progress has been made, China needs to focus on increasing efforts in the first "95" target to further reduce HIV transmission rates and improve overall outcomes.
Using a comprehensive molecular epidemiological approach, we characterized the transmission dynamics of HIV-1 among the MSM population in Tianjin, China. Our findings revealed that 38.56% (386/1001) of individuals clustered across 109 molecular transmission clusters (TCs), with MSM aged 50 and below being the group most commonly transmitting HIV-1.
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- HIV and syphilis outbreaks predominantly affect men who have sex with men (MSM), but there has been limited research on their incidence rates and trends in this group in China.
- A decade-long study in Tianjin reveals a decreasing rate of HIV incidence alongside an increasing rate of syphilis in MSM.
- The findings highlight the need for targeted public health interventions to address the shared risk factors for both infections within this community.
What Is Already Known About This Topic?: Acquired immunodeficiency syndrome (AIDS) represents a significant public health challenge globally, not only inflicting harm on the health of individuals but also placing a considerable economic strain on society.
What Is Added By This Report?: This study represents the inaugural report on the potential reduction in economic burden attributable to human immunodeficiency virus (HIV) prevention strategies in Tianjin. Between 2011 and 2022, it is estimated that effective measures could prevent 2,965 new HIV infections and avert 658 deaths, resulting in an economic benefit of approximately 14.
Background: In Tianjin, China, there is a relatively high prevalence of HIV in men who have sex with men (MSM). The number of HIV cases in Tianjin is also increasing. We investigated the HIV molecular transmission network, genetic tropisms, and drug resistance mutations in Tianjin.
View Article and Find Full Text PDFChina has 747,000 confirmed HIV/AIDS cases and sexual transmission between men who have sex with men (MSM) is the most prevalent mode of transmission. Our study aims to (a) examine HIV prevalence and behavioral risk factors for HIV infection among 1900 MSM recruited from a community-based organization in Tianjin, China, and (b) describe HIV treatment outcomes for those diagnosed with HIV. We used multivariable logistic regression to identify which socio-demographics and behaviors were associated with HIV infection.
View Article and Find Full Text PDF[Epidemic analysis of HIV-1 incidence using BED-CEIA assay in Tianjin, China, 2010].
Zhonghua Yi Xue Za Zhi
April 2013
Objective: To explore the epidemic characteristics of HIV-1 recent infection among high-risk populations in Tianjin and to provide reasonable evidence for intervention strategy.
Method: Blood samples were detected using BED-CEIA to identify recent HIV-1 infection, and HIV/AIDS cases in Tianjin 2010 were collected to analyze epidemic data.
Results: 349 of reported HIV/AIDS cases were confirmed from total 777 207 people.
[Survey on recent infection of human immunodeficiency virus among men who have sex with men in Tianjin during 2008 - 2009].
Zhonghua Liu Xing Bing Xue Za Zhi
November 2011
Objective: To study the situation of HIV infections among men who have sex with men (MSM) in Tianjin during 2008 - 2009 and to provide reasonable evidence for intervention strategy.
Methods: Transect investigations in MSM were conducted three times during 2008 - 2009. Blood samples were collected and detected to identify the recent HIV infection with IgG-capture BED-enzyme immunoassay (BED-CEIA) before HIV incidence was estimated.