Publications by authors named "Tiebiao Liang"
Article Synopsis
- Splicing mutations are found in 9.1% of cardiac involvement cases, though their clinical impact, especially concerning dilated cardiomyopathy (DCM) and sudden cardiac death (SCD), has not been thoroughly studied.
- This study aims to explore the clinical features and pathogenic traits of splicing mutations in DCM and SCD by analyzing a novel family case and summarizing data from 17 families, finding a notable incidence of SCD among affected individuals.
- The research indicates that patients with DCM exhibit distinct clinical patterns compared to non-DCM patients, with potential benefits of pacemaker implantation in reducing SCD risk, and includes specific findings regarding an LMNA mutation linked to severe pathogenic effects and altered gene expression
Background: Coronary heart disease (CHD) is the leading cause of human death worldwide. Genetic factors play an important role in the occurrence of CHD. Our study is designed to investigate the influence of CYP7B1 polymorphisms on CHD risk.
View Article and Find Full Text PDFBackground: Coronary heart disease (CHD) is a disease that seriously harms human health. Genetic factors seriously affect the CHD susceptibility. The CYP20A1, CYP4F2 and CYP2D6 are important drug metabolism enzymes in the human body.
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