Effects of insulin resistance on myometrial growth.

To observe the effects of insulin resistance on gonadal steroid hormone stimulation and the myometrial growth of female rats in order to elucidate the relationship between insulin resistance and the development of uterine leiomyomas. We divided 180 nonpregnant female Wistar rats into three groups as follows: group A, as the control group; group B, as the "model by exogenous sex hormone" group; and group C, as the "model by exogenous sex hormone plus insulin-resistance" group. All the animals were raised for 16 weeks.

[Influence of heat shock factor 1 gene transfection on the expression of inflammatory mediators in macrophages induced by burn serum].

Objective: To investigate the influence of heat shock factor1 (HSF1) on gene expression of inflammatory mediators in RAW264.7 murine macrophage cells induced by burn serum.

Methods: Sera were separated from blood of normal rats and rats with severe burns, and the recombinant vector pcDNA3.