Publications by authors named "Tie-Cheng Wu"
[Analysis of influencing factors to metastasis in sentinel lymph nodes and non-sentinel lymph nodes in breast cancer].
Zhonghua Zhong Liu Za Zhi
October 2013
Objective: To explore the relevant factors influencing sentinel and non-sentinel lymph node (SLNM, NSLNM) metastases in breast cancer.
Methods: The clinicopathological data of 283 women with breast cancer who underwent sentinel lymph node biopsy from July 2010 to August 2011 in the Cancer Institute and Hospital at Chinese Academy of Medical Sciences were reviewed retrospectively, and the relevant factors affecting sentinel and non-sentinel lymph node metastases were analyzed.
Results: Univariate analysis showed that age, menopause status, tumor size, pathological type and intravascular tumor thrombus were associated with SLNM metastasis (all P < 0.
Background: We examined the effect of aspirin on survival following resection for squamous cell carcinoma (SCC) of the esophagus or adenocarcinoma of the gastric cardia.
Methods: Patients who underwent esophagectomy for these cancers between May 2000 and December 2002 were allocated to one of three groups and given daily either a low dose of aspirin, placebo, or no tablets.
Results: The 5-year survival for all patients on aspirin (445) was 51.
Article Synopsis
- The study looked at patients with a type of cancer called adenocarcinoma of the ampulla of Vater, focusing on how cancer spreading into the common bile duct affects outcomes after surgery.
- Out of 102 patients, some had cancer spread to the bile duct, which was linked to a higher chance of the cancer spreading further and had worse survival rates compared to those without bile duct involvement.
- The overall survival for patients with bile duct infiltration was about 36 months, while it was 49 months for those without it, showing that bile duct invasion can make the cancer harder to treat.
Although non-steroidal anti-inflammatory drugs (NSAIDs) have been demonstrated to have cancer-preventive effects and induce apoptosis of cancer cells, the mechanism of their effects is not clearly known. We studied the mechanism in human esophageal cancer cell line TE13. The esophageal squamous cell carcinoma cell line TE-13 was cultured with NS-398 at different concentrations or for different times.
View Article and Find Full Text PDF[Challenges and development tendency of neoadjuvant therapy for gastric cancer].
Zhonghua Wei Chang Wai Ke Za Zhi
March 2008
Our previous study showed that aspirin induced apoptosis of esophageal cancer cells in vitro by inhibiting the pathway of NF-kappaB downstream regulation of cyclooxygenase-2. The purpose of this study was to determine if similar changes occurred in vivo in the tumors of patients with SCC of the esophagus who were given a preferential COX-2 inhibitor, meloxicam. Fifty-three patients who had an esophagectomy for SCC were allocated randomly to either a Treatment group (n = 25) or a control group (n = 28).
View Article and Find Full Text PDF[Surgical effect of malignant tumor of body and tail of the pancreas: compare with pancreatic head cancer].
Zhonghua Wai Ke Za Zhi
January 2007
Objectives: To investigate the clinical-pathological characteristics and surgical prognosis of malignant tumor of pancreatic body and tail.
Methods: A retrospective study was accomplished on clinical manifestation, pathological behavior and postoperative survival in 106 patients with malignant tumor of pancreatic body and tail in single institution from Jan 1980 to Dec 2003, and compared these with 451 patients with malignant pancreatic cancer.
Results: There were significant differences in the following parameters (malignant tumor of the body and tail vs those of the head) between the two tumors: (1) the complaints of pain (0.
[Prevention and surgical treatment of pelvic local recurrence after curative resection colon carcinoma].
Zhonghua Wei Chang Wai Ke Za Zhi
May 2006
[Risk factors for recurrence and metastasis after radical anterior resection for rectal cancer].
Zhonghua Wei Chang Wai Ke Za Zhi
May 2006
Article Synopsis
- The study looked at what makes rectal cancer come back or spread after surgery in 957 patients between 1983 and 2000.
- Out of those patients, 150 had their cancer come back or spread, mostly to the pelvis, liver, or lungs, with an average time of 18 months before it happened.
- Important risk factors that could lead to the cancer returning include having a family history of cancer, high levels of a certain blood marker, and the cancer being more advanced or spreading to lymph nodes.
[Therapeutic options and prognosis of synchronous multiple primary colorectal carcinomas].
Zhonghua Zhong Liu Za Zhi
July 2005
Objective: To investigate the therapeutic principles and prognosis of synchronous primary colorectal carcinomas (SCC).
Methods: The data of 66 SCC patients surgically treated from 1984 to 2003 were retrospectively reviewed.
Results: The synchronous primary colorectal carcinomas were diagnosed and resected simultaneously in 65 patients except one that was misdiagnosed.
Objective: To analyze the differences and relationships among periampullary cancers.
Methods: A retrospective study was accomplished on the clinical manifestation, pathological behavior and postoperative survival of 631 patients with periampullary cancer hospitalized from Jan 1980 to Dec 2003.
Results: The characteristics of different periampullary cancers, in the order of carcinoma of head of pancreas (n = 352), carcinoma of common bile duct (n = 42), carcinoma of Vater's ampulla (n = 189), and duodenal cancer (n = 48) were as follows: (1) the mean duration of symptoms were 11.