The very large electrode array for retinal stimulation (VLARS)-A concept study.

Objective: The restoration of vision in blind patients suffering from degenerative retinal diseases like retinitis pigmentosa may be obtained by local electrical stimulation with retinal implants. In this study, a very large electrode array for retinal stimulation (VLARS) was introduced and tested regarding its safety in implantation and biocompatibility. Further, the array's stimulation capabilities were tested in an acute setting.

Relationships Between Spatial Contrast Sensitivity and Parafoveal Cone Density in Normal Subjects and Patients With Retinal Degeneration.

Background And Objective: To investigate the relationship between spatial contrast sensitivity (CS) and parafoveal cone density (PCD).

Patients And Methods: Fifteen healthy individuals (mean age: 26.1 years ± 4.

Relationship between reading performance and saccadic disconjugacy in patients with convergence insufficiency type intermittent exotropia.

Purpose: To determine the relationship between re-reading the same line and saccadic disconjugacy in patients with convergence insufficiency-type intermittent exotropia [CI-type X(T)].

Methods: Eight patients with CI-type X(T) and ten healthy orthophoric individuals were studied. Video-oculography was used to assess the eye movements during the reading of a Japanese novel displayed on a 23-in.

Surgical feasibility and biocompatibility of wide-field dual-array suprachoroidal-transretinal stimulation prosthesis in middle-sized animals.

Purpose: To investigate the safety and efficacy of a newly-developed wide-field dual-array suprachoroidal-transretinal stimulation (STS) prosthesis in middle-sized animals.

Methods: The prosthesis consisted of two arrays with 50 to 74 electrodes. To test the feasibility of implanting the prosthesis and its efficacy, the prosthesis was implanted for 14 days into two rabbits.

Slow Cone Reflectance Changes during Bleaching Determined by Adaptive Optics Scanning Laser Ophthalmoscope in Living Human Eyes.

To investigate the changes in the reflectance of human cone photoreceptors by an adaptive optics scanning laser ophthalmoscope (AO-SLO) during photobleaching. A custom-built AO-SLO with an observation light of 840-nm was used to measure the cone densities and the reflectance changes during bleaching by 630 nm red light emitting diodes. Measurements were made at 1° and 3° temporal to the fovea within an area of 1° × 1° in 8 eyes of 8 normal subjects.