Papain functionalized Prussian blue nanozyme colloids of triple enzymatic function.

Prussian blue nanozymes were surface engineered with papain enzyme to develop processable nanoparticle dispersions with antioxidant and hydrolytic activities for biocatalytic applications. Enzyme coating improved the colloidal stability of the nanozymes and the obtained papain-Prussian blue hybrid showed remarkable peroxidase ( = 8.82 × 10 M s, = 12.

Coamplified Nanozyme Cocktails for Cascade Reaction-Driven Antioxidant Treatments.

Antioxidant nanozymes are powerful tools to combat oxidative stress, which can be further improved by applying nanozyme mixtures of multiple enzymatic function. Here, cocktails of Prussian blue (PB) nanocubes and copper(II) exchanged ZSM-5 zeolites (CuZ) with enhanced reactive oxygen species (ROS) scavenging activity were developed. Surface functionalization of the particles was performed using polymers to obtain stable colloids, i.

Engineering inorganic nanozyme architectures for decomposition of reactive oxygen species.

Enzyme-mimicking nanomaterials (nanozymes) with antioxidant activity are at the forefront of research efforts towards biomedical and industrial applications. The selection of enzymatically active substances and their incorporation into novel inorganic nanozyme structures is critically important for this field of research. To this end, the fabrication of composites can be desirable as these can either exhibit multiple enzyme-like activities in a single material or show increased activity compared to the nanozyme components.

Aptamer Clicked Poly(ferrocenylsilanes) at Au Nanoparticles as Platforms with Multiple Function.

Aptamers are widely used in biosensing due to their specific sensitivity toward many targets. Thus, gold nanoparticle (AuNP) aptasensors are subject to intense research due to the complementary properties of aptamers as sensing elements and AuNPs as transducers. We present herein a novel method for the functional coupling of thrombin-specific aptamers to AuNPs via an anionic, redox-active poly(ferrocenylsilane) (PFS) polyelectroyte.