QTL mapping and candidate gene analysis reveal two major loci regulating green leaf color in non-heading Chinese cabbage.

Two major-effect QTL GlcA07.1 and GlcA09.1 for green leaf color were fine mapped into 170.

High-altitude cerebral hypoxia promotes mitochondrial dysfunction and apoptosis of mouse neurons.

Introduction: Neuronal cell death is an important factor in the pathogenesis of acute high-altitude cerebral hypoxia; however, the underlying molecular mechanism remains unclear. In this study, we tested if high-altitude hypoxia (HAH) causes neuronal death and mitochondrial dysfunction using various and approaches.

Methods: Acute high-altitude cerebral hypoxia was induced by hypobaric hypoxia chamber in male mice.

Velvet Antler Ameliorates Cardiac Function by Restoring Sarcoplasmic Reticulum Ca-ATPase Activity in Rats With Heart Failure After Myocardial Infarction.

Velvet antler (VA; cornu cervi pantotrichum), a well-known traditional Chinese medicine, has been shown to exert cardioprotective effects. The purpose of this study was to investigate the effect of VA on heart failure (HF) caused by ischemia-reperfusion, and explore its possible mechanism from the regulation of sarcoplasmic/endoplasmic reticulum Ca-ATPase 2 alpha (SERCA2a). A rat model of HF was established by ligating the left anterior descending coronary artery of male Sprague-Dawley rats ( = 88).